polygenic disease


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Noun1.polygenic disease - an inherited disease controlled by several genes at once
diabetes - a polygenic disease characterized by abnormally high glucose levels in the blood; any of several metabolic disorders marked by excessive urination and persistent thirst
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The previous concept that genetic polymorphisms are in the exon region and can lead to variations in the amino acids in vital parts of the protein causing functional alterations and that the polymorphism in the regulation region might affect the level of gene expression, indicates the physiological significance of these two types of SNPs, and forms the core of the study of the susceptibility genes in polygenic disease.
Hyperlipidemia (HL) is a polygenic disease triggered by a combination of genetic and environmental factors.
Below mentioned things are the useful for providing energy to the body when you are suffering from Polygenic disease.
Osteoporosis is a complex polygenic disease that results from an interaction between non-genetic factors and several different genes (Gueguen et al.
MS is a complex polygenic disease, and the dissection of its genetic background is very complicated because of the combinatorial possibilities of gene-gene interactions.
Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease.
Type 2 diabetes mellitus is a polygenic disease characterized by insulin resistance followed by a failure of pancreatic [beta] cells to adequately compensate for this resistance despite increased insulin secretion.
The detection and mapping of the locations of the genes predisposing to a polygenic disease would require hundreds of thousands of DNA markers.
Many of these reported associations are not very strong and it would be logical to assume that since MTX acts on several metabolic pathways in a polygenic disease like RA, a single genetic locus would probably be unable to adequately predict the response.
The pathogenesis of type II diabetes mellitus: a polygenic disease.
Differentiated thyroid carcinoma: A polygenic disease.