polygenic disorder


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Related to polygenic disorder: Autosomal disease, multifactorial disease
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Noun1.polygenic disorder - an inherited disease controlled by several genes at once
diabetes - a polygenic disease characterized by abnormally high glucose levels in the blood; any of several metabolic disorders marked by excessive urination and persistent thirst
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References in periodicals archive ?
Vitiligo is a multifactorial polygenic disorder characterized by patchy depigmentation which is often progressive2,3,13.
Diabetes mellitus (DM) is a polygenic disorder. It may also be called a heterogeneous abnormality.
[18] The absence of causes of secondary dyslipidaemia in this severely hypercholesterolaemic group suggests either polygenic disorder, in which multiple polymorphisms of genes are involved in increased production of LDL, or reduced clearance of LDL due to underlying heterozygous FH.
Hence for both the practitioner and patient, it's of reduced importance to label the actual sort of polygenic disorder than it's to grasp the pathologic process of the symptom and to treat it effectively.
Type 2 Diabetes mellitus is a polygenic disorder, caused by a cluster of susceptibility genes.
Molecular genetics studies suggest that ADHD is a multifactorial polygenic disorder with minor contribution from each individual susceptibility gene.
Since hypertension is a polygenic disorder influenced by multiple genes, further association studies and screening of other candidate gene polymorphisms is required to elucidate the precise genetic susceptibility of essential hypertension.