is usually cheaper than the total cost of the individual components, and patient compliance is also enhanced since they only have to take one pill.
The aim of this research programme is to evaluate the potential for pharmacological prevention of ageing-related decline in humans with a polypill
targeting the nutrient-sensing network.
They discussed a wide range of issues related to the advantages of implementing a tele-rehabilitation programme at the home of patients who suffer from heart failure, the cardiac rehabilitation programmes around the globe, the role of physical exercise as a polypill
to prevent and manage almost every chronic disease, the importance of Vitamin D, and more.
They discussed a wide range of issues related to the advantages of implementing a Telerehabilitation programme at the home of patients who suffer from heart failure, the cardiac rehabilitation programmes around the globe, the role of physical exercise as a polypill
to prevent and manage almost every chronic disease, and the importance of Vitamin D, among others.
Strategy to Improve Adherence: Results From the FOCUS Project.
Saleem Yusuf originated the concept of the polypill
more than 10 years ago by proposing to make one simple pill to mitigate the effect of aging on cardiovascular mortality, particularly in the underdeveloped and rapidly aging countries of the world.
Effects of a polypill
(Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomized trial.
The HOPE-3 trial was the first formal study of the polypill
concept of fixed-dose, low-dose combination therapy as a public health tool for primary prevention in an intermediate-risk population without cardiovascular disease.
, which combines two blood pressure drugs, statins and aspirin, was found to lower cholesterol and hypertension, and blood pressure and cholesterol fell by a "modest but highly statistically significant" amount among the polypill
users compared with patients on standard treatments.
This fits with the strategy proposed by Wald and Law in 2000 and in 2003 in the BMJ to take a polypill
containing blood pressure lowering drugs, a statin, and possibly aspirin and folic acid.
We assumed that the polypill
group was prescribed a single pill that included all four-drug components of combination pharmacotherapy (e.
Over 50s, with no history of cardiovascular disease, were given a polypill
containing three blood pressure lowering medicines and a statin for lowering cholesterol.