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Related to polysome: peroxisome


American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) another name for polyribosome
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈpɒl iˌsoʊm)

a complex of ribosomes that lines up along a strand of messenger RNA and translates the genetic code during protein synthesis.
[1960–65; poly- + (ribo) some]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
Regnase-1 destabilizes translationally active mRNAs in the polysome fraction, and translation termination is required for Regnase-1mediated mRNA decay.
Ribosome footprinting and polysome profiling experiments have detected more than 250 genes, including MYC, MDM2, CDK6, and AFR6 that are affected by silvestrol treatment making it a promising drug to treat cancer [146,147].
For instance, the presence of BAP has been linked to enhanced protein synthesis and heightened polysome function.
Several ribosomes can translate an mRNA molecule simultaneously forming a polysome. In prokaryotes translation often begins before synthesis of mRNA is completed; in eukaryotes this does not occur because mRNA is made in the nucleus whereas the ribosomes are located in the cytoplasm.
Current research focuses on optimizing experimental conditions for improved separation of monosome and polysome fractions in infected and control plant cells.
Lytovchenko et al., "Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells," BMC Molecular Biology, p.
The polysome microarray approach, which was originally reported by Zong et al., is the most commonly used method for translatome analysis [13].
Differential regulation of polysome mRNA levels in mouse Hepa-1c1c7 cells exposed to dioxin.
Polysome profile experiments indicate that, under conditions of translational repression, target mRNAs are fully loaded with ribosomes, a number of which are engaged in active translation, suggesting that translation initiation and elongation phases are not compromised.
Developing stages of the Antarctic sea urchin were further analyzed to determine the range of polysome size classes by quantifying the number of ribosomes attached to each mRNA transcript during translation.
Ridley et al., "Differential regulation of polysome mRNA levels in mouse Hepa-1C1C7 cells exposed to dioxin," Toxicology in Vitro, vol.