4], NCL is also an important regulator of posttranscriptional
RNA stability and translation efficiency, and NCL overexpression reduces apoptosis by regulating mRNA stability of apoptotic genes, such as Bcl-2 .
Thus, The formation and composition of an mrnp is important for the posttranscriptional
control of gene expression.
Our results also indicate that inflammation may suppress the expression of AANAT in the ovine pineal gland both at the transcriptional and posttranscriptional
MicroRNAs (miRNAs) are single stranded, short length (21 to 23 nucleotides), non-coding RNA molecules that function as a negative posttranscriptional
regulation mechanism and play a major regulatory role in various mechanisms in developmental biology, physiology and pathology of almost every organ including the cardiovascular system (10-13).
regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C.
Transcriptional and posttranscriptional
regulation, signal transduction and cell-type-specific expression.
Under normal physiological conditions, cyclooxygenase (COX) enzyme expression is under strict control with transcriptional and posttranscriptional
Differential roles of AC2 and AC4 of cassava geminiviruses in mediating synergism and suppression of posttranscriptional
RNAi can silence specific gene expression via the mechanism involved in posttranscriptional
gene down-regulation in which double-stranded RNA triggers the destruction of cognate RNAs.
Edaravone inhibits the induction of iNOS gene expression at transcriptional and posttranscriptional
steps in murine macrophages.
sup] MicroRNAs are noncoding RNAs and regulate posttranscriptional
gene expression by inhibiting mRNA translation or inducing its degradation, [sup] to modulate the expression of target genes to an optimum level, rather than participating in on/off decisions in the inflammatory response.
As a unique second messenger, c-di-GMP has been demonstrated to be involved in a plethora of physiological functions, including motility, biofilm formation, quorum sensing, virulence, and cell cycle, at the transcriptional, posttranscriptional
and post-translational levels (2).