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Related to poxviruses: Orthopoxvirus


n. pl. pox·vi·rus·es
Any of a group of DNA-containing viruses, including those that cause smallpox, cowpox, and other poxlike diseases in vertebrates.


(Pathology) any of the viruses responsible for pox diseases


(ˈpɒksˌvaɪ rəs)

n. pl. -rus•es.
any of various large, brick-shaped or ovoid viruses of the family Poxviridae, including the viruses that cause smallpox and other pox diseases.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.poxvirus - any of a group of viruses that can cause pox diseases in vertebrates
myxoma virus - a poxvirus closely related to smallpox virus; causes benign gelatinous tumors in humans
smallpox virus, variola virus - the virus that causes smallpox in humans; can be used as a bioweapon
animal virus - an animal pathogen that is a virus
References in periodicals archive ?
Tecovirimat (TPOXX) is an antiviral that inhibits a major envelope protein that poxviruses need to produce extracellular virus.
Using systems biology, virology, cell biology, biochemistry, molecular biology and a wide range of microscopy approaches we will unravel the complex interactions between poxviruses and the host cell degradation machinery.
Poxviruses like vaccinia virus, owing to their large genome size, can accommodate a large part of deletion in their genome without compromising their ability to replicate in the cells and can, therefore, insert a number of genes of foreign origin (~25 kb), leading to the production of multivalent vaccines (4,5).
Avian poxviruses (APV) are very large viruses spread worldwide in a variety of hosts.
Foot and Mouth Disease (FMD), Coronavirus and poxviruses are just some of the threats that animals imported into the country can carry.
Poxviruses are supposed to have antagonistic mechanism to innate antiviral immunity a multi-stage process.
The Moredun Research Institute said: "The institute has undertaken work on poxviruses of sheep and cattle for many years, but more recently has extended this to investigate squirrelpox virus which is nearly always fatal in red squirrels and associated with their significant decline in the UK.
Poxviruses are the largest known group of animal DNA viruses.
Bernard Moss, at the US National Institutes of Health, where he continued his work on poxviruses, viral vectors and recombinant virus construction as well as in the replication and egress of vaccinia virus.
They discuss innate antiviral responses in invertebrates and Toll-like receptors (TLR) in vertebrates, as well as the phylogenetic relationship of pathogen sensing, the downstream adaptor molecules, and the functional consequences; nucleic acid sensing pathways, alternative regulator mechanisms of TLR signaling RIG-I-like receptors, the contribution of LGP2 to antiviral immunity, mitochondrial immune signaling complex and DNA sensors, and the complexities of downstream signaling, the adaptor molecules involved, and the regulatory pathways; and the molecular mechanisms by which pathogens such as poxviruses, HIV, and influenza evade host innate immune mechanisms, the viral virulence factors responsible, and their interactions with the innate immune sensors.