pravastatin

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prav·a·stat·in

(prăv′ə-stăt′n)

A statin drug, C ₂₃H₃₆O₇, that blocks the body's synthesis of cholesterol and is used in its sodium form to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[pra-, of unknown origin + -vastatin, statin suffix (from mevastatin, a statin : meva(lonic acid), precursor in the biosynthesis of cholesterol from val(eric acid) + -stat + -in).]

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Noun

pravastatin - an oral drug (trade name Pravachol) administered to reduce blood cholesterol levels; recommended after nonfatal heart attacks

Pravachol

lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

Translations

pravastatin

n pravastatina

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References in periodicals archive ?

The primary prevention study randomized 6,595 middle-aged Scotsmen with an average baseline LDL cholesterol of 190 mg/dL to 4 years of pravastatin at 40 mg/day or placebo.

WOSCOPS: statin 'legacy effect' stands 20 years

pravastatin for D yslipidemia)trial evaluating the effect of LIVALO[sup.

Data Showed After 52 Weeks, LIVALO (pitavastatin) 4 mg Maintained Similar Safety and Significantly Greater LDL-C Reduction Compared with Pravastatin 40 mg in HIV-infected Adults with Dyslipidemia

Rats given daily doses of pravastatin - sold as Pravachol - had to recognise a previously seen object and find a food reward.

Memory loss 'triggered by some statins'

The study led by scientists at the University of Bristol and, tested pravastatin and atorvostatin (two commonly prescribed statins) in rat learning and memory models.

However, the WOSCOPS (West of Scotland coronary prevention study) suggested that patients taking pravastatin had a 30% lower risk of diabetes compared with placebo.

Statins and diabetes

study (Pitavastatin compaREd with praVAstatin In Lowering LDL-C in the U.

LILLY (ELI) & COMPANY - Livalo NLA PREVAIL U S Data Release

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels.

HMG CoA reduction in patients with average cholesterol concentrations

We investigated the effects of pravastatin on serum C-reactive protein (CRP) and neopterin levels in the short term after elective PCI.

Pravastatin therapy fails to suppress post-PCI inflammatory response measured by serum neopterin and CRP levels/ Pravastatin tedavisi serum neopterin ve CRP duzeyleri ile olculen PKG sonrasi inflamasyonu baskilamakta yetersiz kalmaktadir

Each participant received one of five different statins: fluvastatin (Lescol[R]), pravastatin (Mevacor[R]), rosuvastatin (Crestor[R]), simvastatin (Zocor[R]), or atorvastatin (Lipitor[R]).

Statin drugs produce unintentional harmful results

Pitavastatin effectively reduced LDL-C and improved other parameters of lipid metabolism in special patient populations including the elderly(4) and patients at higher cardiovascular risk(5) - Pitavastatin was superior to pravastatin in improving parameters of lipid metabolism in elderly patients (>65 years)(4) - Pitavastatin demonstrated a gradual and sustained increase in high density lipoprotein cholesterol (HDL-C) over the long-term, supported by data from a 52 week extension study(5)

Kowa Announces Successful EU Regulatory Application for Pitavastatin

In HIV patients, treatment of LDL is complicated by the interactions of statins with HAART, and some studies have shown that atorvastatin and pravastatin may be used with ritonavir and saquinavir, but that simvastatin should be avoided (10).

Is statin therapy safe in patients with HIV/hepatitis C coinfection?

The study involved patients who were taking atorvastatin, pravastatin, or simvastatin.