pravastatin

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prav·a·stat·in

(prăv′ə-stăt′n)

A statin drug, C ₂₃H₃₆O₇, that blocks the body's synthesis of cholesterol and is used in its sodium form to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[pra-, of unknown origin + -vastatin, statin suffix (from mevastatin, a statin : meva(lonic acid), precursor in the biosynthesis of cholesterol from val(eric acid) + -stat + -in).]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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Noun

pravastatin - an oral drug (trade name Pravachol) administered to reduce blood cholesterol levels; recommended after nonfatal heart attacks

Pravachol

lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

Translations

pravastatin

n pravastatina

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References in periodicals archive ?

ARBITER: Arterial Biology for Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness.

Statins in stroke prevention/Inmenin onlenmesinde statinler

They emphasize that, with the exception of one study in which new cancer diagnoses were more frequent on pravastatin than on a sugar pill, all large prospective randomized statin trials have shown no difference in the risk of cancer among people taking statins versus those taking a sugar pill.

Lower not necessarily better

Researchers recently analyzed previously published data that followed a randomized trial of pravastatin (Pravachol[R]) in 9,000 patients in New Zealand.

Statin therapy for elderly sees mixed results

One small study looked at the effect of Pravachol (pravastatin), a drug used to lower cholesterol (abstract 77).

Managing lipids

The scientists randomly assigned half the volunteers to get the standard dose of the anticholesterol drug pravastatin or an elevated dose of the more potent statin drug atorvastatin.

Heart patients gain from steep cholesterol drop

When drugs become necessary, we recommend as initial therapy pravastatin or atorvastatin for elevated low-density lipoprotein cholesterol levels and gemfibrozil or fenofibrate when triglyceride concentrations exceed 500 mg/dL."

New guidelines for avoiding heart disease by managing high cholesterol, triglycerides, or related problems in HIV

CHICAGO -- Three years of treatment with pravastatin failed to slow age-related cognitive decline in the first large clinical trial aimed at examining statin therapy's effects specifically in the elderly.

Statin therapy does not slow cognitive decline: pravastatin may reduce coronary deaths. (Elderly Patients)

We've also been able to show that cholesterol-lowering drugs like pravastatin reduce hs-CRP levels.

NEW CLUE TO AN OLD KILLER

You start him on pravastatin (Pravachol) 20 mg once daily.

Three HIV-treating physicians express their professional opinions regarding a case scenario

They'll test the effectiveness of a heart drug, Pravastatin, which may also help prevent strokes.

Experts gather in heart attack city

(1) The increased risk was similar for lipophilic (pravastatin, rosuvastatin) and hydrophilic (atorvastatin, simvastatin, lovastatin) statins, although the analysis wasn't adjusted for doses used.

Q / Do statins increase the risk of developing diabetes?

15 in Annals of Internal Medicine (doi:10.7326/M13-2942), found that the average portion of days covered under prescribed statin therapy was 77% for patients started on generic lovastatin, pravastatin, or simvastatin, and 71% for patients started on name brands of these medications (P < .001).