Every patient was evaluated with a thorough preanesthetic
checkup including routine preoperative investigations one day prior to the surgery.
All patients that complied with the inclusion criteria were selected, these criteria being: age between 18 and 65 years, admitted for urgent or elective non-ambulatory surgery under anesthesia and presenting severe postoperative pain in the PACU, having undergone a preanesthetic
assessment, not being pregnant, not having a background of hypersensitivity or allergic reactions to opioids, having signed the informed consent form for voluntary participation in the study, and not having a risk of ASA >III, hypoxemia (oxyhemoglobin saturation <90%), hemodynamic instability, unexplained alteration of alertness due to anesthetic effects, or basic neurological alterations due to psychiatric disorders.
A blood sample was collected for preanesthetic
medication with clonidine: a dose response study.
Pre-surgical evaluation (T1); after preanesthetic
medication (MPA); trans-surgical/ Immediately after hemostasis for the second ovary (T2); after 4 (T3), 24 (T4) and 72 hours from surgical procedures (T5).
3 mg/kg of BW) mixed in a single syringe with 15 mg of ketamine hydrochloride/kg of BW as a preanesthetic
assessment was done the evening before the day of surgery.
All the 60 patients were subjected to an appropriate preanesthetic
In other nonpsychiatric indications, the drug is used in the symptomatic treatment of vomiting and intractable hiccups and in the treatment of severe pain and is associated with antihistamines during preanesthetic
examination the dog appeared slightly nervous but in good physical condition (ASA II).
This allowed for placement of a catheter in the auricular vein and administration of the preanesthetic
drug propofol (2 mg/s, iv).
All patients received diazepam 10mg orally the night before surgery as per preanesthetic