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a.1.(Anat.) Situated in front of the notochord; - applied especially to parts of the cartilaginous rudiments in the base of the skull.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
References in periodicals archive ?
The cleft created by ultimate separation of the prechordal plate and notochordal process is theorized to lead to a potentially sizeable skull base defect as noted in this patient [15].
INTRODUCTION: Notochord is a midline structure extending from primitive streak to prechordal plate and serves as an axial skeleton for the developing embryo (1).
The exposure effects appear to intersect with an early, critical signaling pathway, the canonical Wnt/[beta]-catenin pathway, important in the prechordal plate, in cardiac induction, valve development [24, 44-47], and in placentation [48, 49] and neurogenesis [50-52].
This organizer is constructed through several successive steps: initially, the endodermal organizer -Nieuwkoop center sends signals to specific cells of the dorsal marginal zone into prechordal head mesoderm.