primaquine


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pri·ma·quine

 (prē′mə-kwēn′, -kwĭn, prī′-)
n.
A drug, C15H21N3O, used in its phosphate form as an antimalarial, especially to prevent relapses.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

primaquine

(ˈpraɪməˌkwiːn)
n
(Pharmacology) a synthetic drug used in the treatment of malaria. Formula: C15H21N3O
[C20: from prima-, from Latin prīmus first + quin(olin)e]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pri•ma•quine

(ˈpraɪ məˌkwin)

n.
a viscous liquid, C15H21N3O, used in the treatment of malaria.
[1945–50; < New Latin prīma prime + quin (olin) e]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.primaquine - synthetic antimalarial drug
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

primaquine

n primaquina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
The other major step by the panel was to add primaquine as a sixth option for primary prophylaxis, although it is a secondline drug because of its potentially serious adverse effects.
She was also advised to take primaquine 0.25 mg/kg/day for 14 days.
Subsequently, a screen for glucose-6-phosphate dehydrogenase (G6PD) deficiency was negative (a requirement for primaquine), and a 14-day course of primaquine (30 mg daily) was administered.
Oral quinine sulphate 600 mg TDS was started on Day 4 for a total of 7 days along with a single dose of 45 mg primaquine. Patient was discharged on Day 10 with complete recovery.
He was treated with chloroquine and primaquine and recovered uneventfully.
He was treated with chloroquine and primaquine as an outpatient and recovered.
In vivo therapeutic efficacy of chloroquine alone or in combination with primaquine against vivax malaria in Kolkata, West Bengal, India, and polymorphism in pvmdrl and pvcrt-o genes.
The patient was started a course of oral chloroquine followed by primaquine (30 mg once daily for 14 days).
One such intervention, which is endorsed by the WHO, [44] is to treat all positive malaria cases with a single dose of primaquine. This drug efficiently inactivates gametocytes but in persons with genetically determined glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency of red blood cells, it may cause haemolysis and subsequent anaemia of variable severity.
Chloroquine was unavailable, so the patient was re-treated with oral hydroxychloroquine with an 800-mg loading dose, followed by 400 mg at 6 hours, 400 mg at 24 hours, 400 mg at 48 hours, and a single 45-mg dose of oral primaquine. The parasite count declined rapidly to 37/[micro]L at 28 hours, 191/[micro]L at 49 hours, and 76/[micro]L at 88 hours of treatment.
Therefore, treatment should also include 2 weeks of primaquine to kill parasites in the liver.