pro-inflammatory


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Adj.1.pro-inflammatory - tending to cause inflammation
unhealthy - not in or exhibiting good health in body or mind; "unhealthy ulcers"
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Eating a diet that is high in pro-inflammatory foods is associated with a higher risk of colorectal cancer, according to a study published online Jan.
Aldeyra plans to collaborate with Janssen on the development of novel drugs designed to sequester pro-inflammatory aldehyde mediators, a new class of therapeutic targets.
Reproxalap and other product candidates generated from Aldeyra's aldehyde trap platform sequester and facilitate the degradation of pro-inflammatory aldehyde mediators, a class of small molecule therapeutic targets that are elevated in DED patients.
After administration of zinc, which increases Cd14 levels in a transgenic mouse model, the investigators found less inflammation in the colon and reduced levels of pro-inflammatory cytokines.
Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway.
A meta-analysis published in PLOS One found more evidence of a reduction in pro-inflammatory factors in association with supplementation with marine-derived omega-3 fatty acids.
Monocytes also produce pro-inflammatory cytokines, small molecules that promote an inflammatory immune response.
A team of researchers used a mouse model of stroke to show that microbes in the gut regulate the development of pro-inflammatory immune cells, which migrate from the intestine to the brain after a stroke is induced.
Through the inhibition of these enzymes, TD-1473 interferes with the JAK/STAT signalling pathway and, in turn, modulates the activity of a wide range of pro-inflammatory cytokines.
The treatment tends to regulate cytokine expression, increasing anti-inflammatory cytokines such as IL-10 and decreasing pro-inflammatory cytokines such as IL-2 and IL-8.
High levels of the pro-inflammatory marker measured in this study and poor blood vessel function are some of the key contributors to the development of CVD.
Our study has implicated a subset of B cells, the GM-CSF producing B cells, as a key contributor in the pro-inflammatory immune cells responses at play in MS," explained Dr.