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A phenothiazine drug, C20H24ClN3S, used to treat schizophrenia and anxiety and to stop or prevent vomiting.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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Noun1.prochlorperazine - antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomiting
antiemetic, antiemetic drug - a drug that prevents or alleviates nausea and vomiting
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References in periodicals archive ?
Global Meniere's Disease Drug Market -By Type ( Classic, Vestibular and Bilateral), Mechanism of Action (Antihistamines, Benzodiazepines, Antinausea, Diuretics, Antibiotics, Steroids and Others), Drugs (Meclizine, Diazepam, Prochlorperazine, Hydrochlorothiazide, Gentamicin, Dexamethasone and Others), Devices (Hearing Aid, Meniett device), Treatment (Medications, Therapy or Hearing Aids, Surgery), Route of Administration (Oral, Intravenous, Intratympanic and Others), Distribution Channel (Online Pharmacy, Direct Tenders, Retailers and Others), End-Users (Hospitals, Homecare, Specialty Clinics, Others), Geography (North America, Europe, South America, Asia-Pacific, Middle East and Africa) - Industry Trends and Forecast to 2026
The Competition and Markets Authority (CMA) said it had provisionally found that Alliance, Focus, Lexon and Medreich had agreed not to compete for the supply to the NHS of prochlorperazine 3mg dissolvable or "buccal" tablets, an anti-nausea and dizziness medicine.
The CMA noted that the price of the prochlorperazine drug then rose from GB6.49 per 50 tablets to GBP51.68 between December 2013 and December 2017.
In subsequent analyses, the authors found that among patients with affective disorders, only current use of medium--to high-potency FGAs (haloperidol, prochlorperazine, and trifluoperazine) was associated with a significantly increased risk of seizures (adjusted odds ratio: 2.51, CI, 1.51 to 4.18) compared with non-users.
May repeat IM x 1 * Promethazine 25 mg IM (do not give IV!) or prochlorperazine 10 mg IV for nausea and/or vomiting, every 2 hours as needed * Atropine 0.5 mg IV for hypersalivation x 1 * Hydralazine 5mg IV given slowly over one minute for a pregnant patient who has severe preeclampsia or eclampsia and who has high blood pressure.
10 mg prochlorperazine (Compazine) 1 hour before the exam.
Her symptoms were attributed to side effects from eculizumab and resolved after treatment with prochlorperazine, ketorolac, diphenhydramine, and intravenous fluids.
In a randomized, double-blind, placebo controlled study comparing the efficacy of metoclopramide, prochlorperazine and saline (placebo) in acute migraine attack, metoclopramide was reported as an effective treatment.7 In this study, the median VAS was 8.5 mm at the beginning (IQR: 7.0-10.0 mm), and 5.6 mm at 60th minute (34% change) in the metoclopramide group.
Extrapyramidal reactions to ondansetron: cross-reactivity between ondansetron and prochlorperazine? Anesth Analg.
Recommend antiemetics, such as diphenhydramine, ondansetron, and prochlorperazine for management of nausea and vomiting.
A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.