(redirected from procoagulants)
Also found in: Medical, Encyclopedia.


1. The precursor of any of various blood factors necessary for coagulation.
2. An agent that promotes the coagulation of blood.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
[3] Pancreatic cancer is associated with an increase in procoagulants such as tissue factor, thrombin, and fibrinogen.
In addition to anticoagulant and thrombolytic therapy, new targeted drugs and treatments must be perfected based on the progress of PTE animal models and research methods, as well as on integrating, the involvement of anticoagulants, procoagulants, fibrinolytics, and the immune system, rather than focusing solely on the thrombus.
Increased levels of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis.
Neuroendothelial imbalance of vasoconstriction and vasodilatation, structural abnormalities of the vasculature, and intravascular factors such as platelet activation, procoagulants, and oxidative stress are the predominant factors that affect the microvasculature and cause critical ischemia.
Hypercoagulation can be due to procoagulants in the venom, such as arginine, esterase and hydrolase, and consumption coagulopathy phase--DIC.
Tissue factor (TF) is a 47kDa transmembrane glycoprotein receptor of factor VII/VIIa (fVIIa), a critical regulator of tissue hemostasis and one of the body's most potent procoagulants [1].
No topical or systemic procoagulants, wound drainage catheters, or cell salvage methods were used in any patient.
Cancer generates a prothrombotic state through the release of procoagulants, such as tissue factor (TF) and cancer procoagulant, with a further enhancement of the hypercoagulable state due to underlying clinical conditions.
Antiphospholipids are procoagulants that prolong the aPTT test.
* Excess procoagulants. Two forms of hereditary thrombophilia increase procoagulant activity.
(11) Current transfusion protocols emphasize fresh whole blood and procoagulants rather than crystalloids to restore organ perfusion, prevent the dilution of clotting factors, and avoid hypothermia.