M2 PHARMA-March 8, 2018-V ClinBio and Camargo Team to Develop
Prodrug Technology Platform
and global intellectual property estate governing its portfolio of
prodrug product candidates with the receipt of an initial patent issued for KP606, an oxycodone
prodrug, as well as an additional composition of matter patent to enhance the existing family of patents related to KP511, a
prodrug of hydromorphone.
A
prodrug is a compound that, after administration, is metabolized in the body into an active drug.
a non- steroidal anti-inflammatory drug (NSAID), it is desirable to design its
prodrug [1-4] by converting its carboxylic acid into ester.
French researchers have introduced a new approach in Angewandte Chemie: the enzyme B-galactosidase releases the active drug from an inactive precursor, known as a
prodrug, which only can be taken up by tumor cells.
Cascade
Prodrug was one of five companies that gave a 10-minute pitch on Thursday to a group of 30 investors - the "angels" of the conference.
In a new approach, the group from the University's Departments of Chemistry and Biochemistry and Biological Sciences and the Friemann Life Sciences Centre, used a
prodrug strategy to address this issue.
A
prodrug is a compound administered in an inactive form then metabolised in the body into an active drug.
Under the terms of the agreement, Eisai shall grant Brain Factory the exclusive rights to develop, commercialize, and sublicense ravuconazole
prodrug in Japan as an ethical antimycotic for treating all types of fungal infections with the exception of Chagas disease.
Byline: Authorities seize 158,000 capsules of synthetic
prodrug Captagon.
The most recent approval of the company's supplemental new drug application makes Vyvanse the only daily
prodrug stimulant approved as ADHD therapy for adults, according to Shire.
Known as GDEPT (Gene-Directed Enzyme
Prodrug Therapy), the treatment uses a virus to attack cancer cells.
