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A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death before the age of 20. Also called Hutchinson-Gilford progeria syndrome.

[pro- + Greek gēras, old age; see geriatrics + -ia.]


(Pathology) med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age
[C20: from pro-2 + Greek gēras old age]


(proʊˈdʒɪər i ə)

a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person.
[1900–05; < Greek progḗr(ōs) prematurely old (pro- pro-2 + -gēros, adj. derivative of gêras old age) + -ia]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.progeria - a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies


n progeria
References in periodicals archive ?
Nabi and Razia only found out about progeria in 1995 after seeing an expert - who told them it was incurable.
By adopting this strategy they have succeeded in identifying pathogenic mutations responsible for this disease in the ERCC4 gene, which had already been linked to two other rare diseases: xeroderma pigmentosum and a type of progeria.
In P , he cast the actor as a 13- year- old suffering from the rare illness, progeria.
The most severe disorders linked to this mutation include Hutchinson Gilford Progeria Syndrome (HGPS), a lethal disease that causes premature ageing in children and affects one in four to eight million newborns worldwide.
It was used in experiments on children suffering from a rare genetic condition called Hutchinson-Gilford Progeria Syndrome where ageing is accelerated.
The show picks up the 13-year-old's story as she deals with progeria, a rare condition causing old age.
Chances are you'll have seen her before because Hayley is one of the most recognisable faces of progeria, the genetic mutation she's helped to raise awareness of by appearing in a series of documentaries for Five.
The show picks up the 13-year-old's story as she deals with progeria, an incredibly rare condition that causes signs of old age in young children.
MONDAY Extraordinary People: Hayley - The 96-year-old Schoolgirl (Five, 9pm) YES, it may sound like a dodgy headline from a dodgy story in The Daily Sport, but it's actually an update on a 12-year-old girl - Hayley Okines - who has progeria, which means she ages eight times faster than she should be doing.
His recent movie, Paa, on the fatal disease progeria, won him critical acclaim.
His laboratory is dedicated to researching both rare and common diseases and has discovered a number of important genes, including those responsible for cystic fibrosis, neurofibromatosis, Huntington's disease, adult onset diabetes and Hutchinson-Gilford progeria syndrome, a dramatic form of premature aging.
Adult stem cells may provide an explanation for the cause of Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).