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A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death before the age of 20. Also called Hutchinson-Gilford progeria syndrome.

[pro- + Greek gēras, old age; see geriatrics + -ia.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pathology) med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age
[C20: from pro-2 + Greek gēras old age]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(proʊˈdʒɪər i ə)

a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person.
[1900–05; < Greek progḗr(ōs) prematurely old (pro- pro-2 + -gēros, adj. derivative of gêras old age) + -ia]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.progeria - a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n progeria
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
"Hutchinson-Gilford Progeria Syndrome or HGPS is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children.
The findings also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
The findings, published June 29 in the journal Stem Cells, also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
Researchers have discovered a link between deactivation of SIRT1 and progeria, a condition that results in premature accelerated aging and markedly shortened life span.
About 300 mourners gathered to pay tribute to the youngster, who was just 17 when she lost her battle with the rare ageing disorder progeria this month.
Sarah Geronimo goes to Bulacan to thank her young fan Rochelle, who is afflicted with progeria.
COLLEGE PARK, Md., June 2, 2014 -- Children with progeria, a rare disorder that causes premature aging, die in their teens of ailments that are common in octogenarians: heart failure and stroke.
A case report of 6-year-old boy with progeria syndrome, with marked cardiac complications is presented.
Ali was born with progeria, a genetic condition that ages his body eight times faster than normal.
It turned out that Sam has Hutchinson-Gilford progeria syndrome, an extremely rare genetic disease that affects about one in 4 million to 8 million children.
Eiger is preparing an NDA and MAA for lonafarnib to treat Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) and Progeroid Laminopathies.
The new genome-editing technology could be expanded for use in a broad range of gene mutation conditions such as Huntington's disease and the rare premature aging syndrome, progeria.