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Related to progestin: progesterone


Any of several synthetic progestational substances that mimic some or all of the actions of progesterone, used as contraceptives either alone or in combination with estrogen, and with estrogen in hormone replacement therapy.


(proʊˈdʒɛs tɪn)

also pro•ges•to•gen

(-ˈdʒɛs tə dʒən)

any substance having progesteronelike activity.
[1925–30; pro-1 + gest (ation) + -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.progestin - any of a group of steroid hormones that have the effect of progesterone
sex hormone, steroid hormone, steroid - any hormone affecting the development and growth of sex organs
Lipo-Lutin, progesterone - a steroid hormone (trade name Lipo-Lutin) produced in the ovary; prepares and maintains the uterus for pregnancy
megestrol, megestrol acetate - a synthetic progestational compound used to treat endometrial carcinoma
norethandrolone, norethindrone, norethindrone acetate, Norlutin - a synthetic progestational hormone (trade name Norlutin) used in oral contraceptives and to treat endometriosis
norethynodrel - a progesterone derivative used in oral contraceptives and in the control of menstruation and the treatment of abnormal uterine bleeding
norgestrel - synthetic progestin used in oral contraceptives
medroxyprogesterone, Provera - a progestin compound (trade name Provera) used to treat menstrual disorders
References in periodicals archive ?
Animal and laboratory data suggest a range of possible biologic mechanisms for an association between hormonal contraceptive use and HIV acquisition, potentially related to the progestin component, including hormonally mediated changes in the vaginal epithelium and alterations in local and systemic immune responses (8,9).
M2 PHARMA-June 27, 2017-Xenetic Biosciences Enrolls Patients in Study of XBIO-101 in Conjunction with Progestin for Endometrial Cancer
The company will start its Phase 2 clinical study of Virexxa in conjunction with progestin therapy for the treatment of endometrial cancer in women with recurrent or persistent disease who have failed progestin monotherapy.
Progestin implants: Implanon and Nexplanon (Merck) are both implants containing the active metabolite of desogestrel, a progestin.
In the estrogen-progestin trial, 16 608 women with an intact uterus were assigned to oral estrogen plus progestin [0.
Findings from the WHI study in 2002 indicated a greater risk of breast cancer and heart disease among women who used a combination of estrogen and progestin as hormone replacement therapy in comparison with those who received a placebo.
Some birth control pills, called mini-pills, contain only progestin.
30 ( ANI ): Estrogen plus progestin use has been linked with increased breast cancer incidence, a study has found.
Using menopausal hormone therapies to relieve symptoms in postmenopausal women has long raised difficult questions: Is the combination of estrogen and progestin better or worse than estrogen alone?
Fifty-six premenopausal women (mean age, 47 years) with abnormal bleeding due to non-atypical endometrial hyperplasia were randomly assigned to receive, in double-blind fashion, genistein (as genistein aglycone, 54 mg/day), norethisterone acetate (a progestin, 10 mg/day on days 16-25 of the menstrual cycle), or placebo for six months.
These are mostly low-grade adenocarcinomas with a good prognosis and well-described risk factors such as nulliparity, obesity, hyperoestrogenism, other cancers, tamoxifen use and inadequate progestin cover when taking oestrogens.

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