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Fertilizasyon sonrasi ilk olarak; protamin ile paketlenmis olan bolgeler, maternal histonlar ile yeniden paketlenmektedir (8).
2) Insulin (Regular, neutral protamin hagedorn or both) was started at randomisation visit according to fasting and 2-hour postprandial plasma glucose values.
and reversed by protamine hydrochloride at the end of the procedure (Protamin ICN, Mefar A.S., Istanbul, Turkey).
The heparin was reversed by the administration of protamin. We used a different target ACT for both procedures, because there were different indications for the use of anticoagulation.
Histon hiperasetilasyonu haploid spermatidlerin histon protamin degiiminden sorumludur.
Hayvanlarda Tip I diyabet sonrasi ketoasidoza ve kilo kaybina bagli mortaliteyi onlemek amaciyla; STZ ve alloksan uygulamasini takiben belli bir sure protamin cinko (65) veya ultralente insulin (66) gibi uzun etki sureli insulin preparatlarinin gunluk 2 IU dozunun enjeksiyonu onerilmektedir.