proteinosis


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Related to proteinosis: lipoid proteinosis
Translations

pro·tein·o·sis

n. proteinosis, acumulación en exceso de proteínas en los tejidos.
References in periodicals archive ?
Serum KL-6 levels were elevated in interstitial pneumonia, hypersensitivity pneumonitis, tuberculosis, sarcoidosis, and pulmonary alveolar proteinosis. It was also observed in patients with RA-ILD (11, 12).
Molgradex for autoimmune pulmonary alveolar proteinosis (aPAP)
M2 PHARMA-June 17, 2019-Savara's IMPALA Phase 3 Study of Molgradex for the Treatment of Autoimmune Alveolar Pulmonary Proteinosis Fails to Meet Primary Endpoint
1d), confirming the diagnosis of alveolar proteinosis. The whole hole-lung lavage was performed for both lungs sequentially.
The authors estimated the occupational burden of these lung diseases: Asthma, 16 per cent, chronic obstructive pulmonary disease (COPD) 14 per cent, chronic bronchitis 13 per cent, idiopathic pulmonary fibrosis 26 per cent, hypersensitivity pneumonitis19 per cent, sarcoidosis and other granulomatous disease 30 per cent, pulmonary alveolar proteinosis 29 per cent, community-acquired pneumonia (in working-age adults) 10 per cent, and tuberculosis (in silica dust-exposed workers), 2 per cent.
Based on the experience of the authors, the cases address non-malignant and malignant airway obstruction, then technical challenges in interventional bronchoscopy, such as fistulation, bleeding, copious secretions, critical airway obstruction, rigid tube coring and dilatation, flexible forceps dilatation, stenting, and pulmonary alveolar proteinosis. The book ends with videos of rigid bronchoscope intubation and comments based on the cases.
A specific diagnosis should be reported (eg, Langerhans cell histiocytosis, lymphangioleiomyomatosis, pulmonary alveolar proteinosis); if no specific pattern is identified (either normal lung or unclassifiable fibrosis), a descriptive diagnosis could be made.
IMPALA is a pivotal Phase 3 clinical study evaluating Molgradex, an inhaled formulation of recombinant human granulocyte-macrophage colony-stimulating factor, for the treatment of autoimmune pulmonary alveolar proteinosis, or aPAP.
Lipoid proteinosis (LP) is a very rare autosomal recessive genodermatoses whose true incidence is not known.
HANNOVER, Germany, August 9, 2018 -- Hereditary pulmonary alveolar proteinosis (herPAP) is a rare disease characterized by the slow build-up of lipoprotein material in the lungs due to the failure of highly specialized cells called macrophages, which usually eat away this material from the pulmonary air-space.
High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood 2004;103:1089-98.