proton-pump inhibitor


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proton-pump inhibitor

n
(Pharmacology) any of a group of drugs used to treat excessive secretion of acid in the stomach and any resulting ulcers. They block the enzyme (proton pump) in the cells of the gastric glands that secrete hydrochloric acid
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease--where next?
Q I have gastroesophageal reflux disease (GERD), and take an over-the-counter H2 blocker to ease my heartburn--but would a proton-pump inhibitor be more effective?
Statins, anticoagulants (e.g., clopidogrel, aspirin), and supplements made up the majority of the dangerous combinations seen--for example, clopidogrel used in combination with the proton-pump inhibitor omeprazole, or aspirin, is linked to an increased risk for heart attacks, bleeding complications, and death.
Intragastric pH With oral vs intravenous bolus plus infusion proton-pump inhibitor therapy in patients with bleeding ulcers.
For the study, researchers at RTI International, University of Michigan, and University of North Carolina at Chapel Hill used a Markov model to compare the costs and outcomes of prescribing low-dose aspirin alone, aspirin plus a proton-pump inhibitor, or no treatment for coronary heart prevention.
Six months after the wedding, she was seen by an otolaryngologist, who diagnosed reflux laryngitis and prescribed a proton-pump inhibitor and voice therapy.
Of the 2,560,420 prescriptions for nonselective NSAIDs, only 1,215,762 (47.5%) had concomitant use of a proton-pump inhibitor or misoprostol.
On April 29, 2005 GlaxoSmithKline announced that a drug-interaction trial of Lexiva (fosamprenavir) with Nexium (esomeprazole, a proton-pump inhibitor, often used to reduce stomach acidity for relief of reflux, the unwanted flow of stomach acid into the esophagus), had found no reduction in the in the blood level of amprenavir.
Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis.
Several months earlier, his primary care physician had started him on a proton-pump inhibitor twice daily.
COPENHAGEN -- Some patients with dyspepsia not caused by reflux or a peptic ulcer who don't respond to a proton-pump inhibitor during the first week of treatment will respond after a few more weeks, based on results from two studies.