pseudogene


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pseu·do·gene

 (so͞o′də-jēn′)
n.
A segment of DNA that resembles a gene but is not functional and usually not transcribed. Pseudogenes often have functional paralogs in the same organism.
Translations
gène silencieux
References in periodicals archive ?
Scientists there conducted genetic analyses and found two notable mutations, one being a "micro-deletion", or a tiny bit missing, in a pseudogene, which do not have the full functionality of regular genes.
Scientists conducted genetic analysis and found two notable mutations: one being a "micro-deletion", or a tiny bit missing, in a pseudogene, which do not have the full functionality of regular genes.
While looking into p53, the researchers found a pseudogene, called leukemia inhibition factor 6 (LIF6).
This includes detecting splicing abnormalities; identifying nonsense-mediated decay; detecting fTameshifi, premature stop, or unexpected indel or exon skipping variants; checking pseudogene reads; and identifying pathogenic variants in 5 '-or 3 '-untranslated regions.
A pseudogene was found for DPPA2 coding sequence which is important in primer design.
Pandolfi, "A coding-independent function of gene and pseudogene mRNAs regulates tumour biology," Nature, vol.
The RecNcil mutation is due to a recombination event with the highly homologous and adjacent GBAP1 pseudogene. This results in the common p.Leu483Pro (c.1448T>C) being coallelic with both the p.Ala495Pro (c.1483G>C) and p.Val499Val (c.1497G>C) sequence variants.
21-hydroxylase enzyme have an active gene and a pseudogene. The rearrangements between these two genes play an important role in the pathogenesis of CAH.
The STRC gene illustrates a gene that cannot be analyzed with standard short-read NGS methods (28 of 29 exons have high homology with a pseudogene, with long stretches being 100% identical across exons and introns between the 2 genes13).
020 A PSEUDOGENE PROVIDES EVIDENCE OF EVOLUTION OF NEW GENETIC INFORMATION BY GENE DUPLICATION FOLLOWED BY FRAMESHIFT MUTATION.
The gene is highly polymorphic, with more than 100 known allelic variations, and has a nearby pseudogene with very high-sequence homology.
Organization and evolution of the flavin-containing mono-oxygenase genes of human and mouse identification of novel gene and pseudogene clusters.