Bakuchiol [(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-l-yl]phenol, a prenylated phenolic monoterpene found in the seeds and leaves of various plants, particularly Psoralea
corylifolia, has been used to treat a broad array of disorders, including skin conditions, in the traditional medical practices of China, Japan, and Korea, as well as Ayurvedic medicine in India.
Wright, The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea
corylifolia and Sanguinaria canadensis, J.
Insecticidal and genotoxic activity of Psoralea
In vitro isolation, elicitation of psoralen in callus cultures of Psoralea
corylifolia and cloning of psoralen synthase gene.
 reported bactericidal activity of bakuchiol (obtained from Psoralea
corylifolia) on different Streptococcus, Enterococcus, and Lactobacillus species and Actinomyces viscosus and P.
Wenget al., "Development of an HPLC method for absolute quantification and QAMS of flavonoids components in Psoralea
corylifolia L," Journal of Analytical Methods in Chemistry, vol.
Psoralidin, for example, a natural phenolic compound found in the seeds of Psoralea
corylifolia, has been seen to inhibit NOTCH1 in breast cancer stem cells and in breast cancer cells, leading to a growth arrest and inhibition of epithelial to mesenchymal transition (EMT) .
Genistein is an isoflavonoid compound present in some edible plants such as alfalfa, soybean, fava bean, psoralea
, pea, green lentil, and lupine .
The eight Chinese herbal medicines used in this study were Chai Hu (Bupleurum), Bai Zhu (Atractylodes), Bai Shao (Paeonia), Gan Cao (Glycyrrhiza), Bu Gu Zhi (Psoralea
), Bo He (Mentha), Fu Ling (Poria), and Shi Gao (Gypsum).
Wu, "Characterization of compounds in psoralea
corylifolia using high-performance liquid chromatography diode array detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry," Journal of Chromatographic Science, vol.
Traditional Chinese Medicine Psoralea