In October 2017, the proteinuria improved (24-h urine protein decreased to 0.828 g/day), but he developed a
purpuric rash on his extremities and torso.
The clinical presentation of a CVA6-related HFMD differs from classic HFMD; the distribution can be more widespread, with
purpuric lesions (10).
Livedoid vasculopathy, also known as atrophie blanche and PURPLE (painful
purpuric ulcers with reticular pattern of the lower extremities) is a rare, chronic vascular condition.
Stevens-Johnson syndrome (SJS) is an acute mucocutaneous process and it is one of the manifestations of severe form of cutaneous eruptions of the skin and mucosal membrane, characterized by severe stomatitis,extensive mucosal necrosis, purulent conjunctivitis and
purpuric macules.
When she was examined by doctors, it was observed that she manifested fever and
purpuric rashes on her feet.
One patient presented with
purpuric coloration in all the fingers, together with a necrotic injury on the fifth finger of the left hand (Figure 2), accompanied by intense pain.
Many skin lesions, such as
purpuric rash, ELE, Henoch-Schonlein purpura, and angioneurotic edema can be seen in FMF cases.
The patient remained febrile with a pulmonary valve murmur of tricuspid regurgitation and
purpuric lesions, tenosynovitis in the left ankle and both wrists, and right knee and interphalangeal polyarthritis.
A
purpuric rash on the extremitieswas noted which was not associated with pain, burning sensation or pruritus.
Bilateral conjunctival hemorrhage and
purpuric eruption on lips were evident.
Purpuric rash with predilection for lower extremities was seen in all 61 patients (100%), either at presentation or during the course of illness.
Lulu Bravo, professor emeritus at the University of the Philippines-Manila College of Medicine, meningococcemia can be so severe as to cause death within 24 hours after initial onset of fever and
purpuric rashes (purplish spots caused by bleeding tiny blood vessels beneath the skin's surface).
