necrosis in a comatose patient with metabolic acidosis.
The publication titled "Magnetic Resonance Imaging-Guided Phase 1 Trial of Putaminal
AADC Gene Therapy for Parkinson's Disease," can be accessed online.
and Optical Involvement After Low Dose of Methanol Exposure: Case Report.
Failure of surgery to improve outcome in hypertensive putaminal
Differential diagnoses include head injury/trauma, lobar extension of a hypertensive putaminal
hemorrhage, a hemorrhagic transformation of an ischemic stroke, an arteriovenous malformation, or a hemorrhagic tumor.
Possible hypotheses for putaminal
T1 hyperintensity include a protein hydration layer in the swollen gemistocytes, putaminal
petechial hemorrhage, demyelination, transient ischemic changes, and localized Wallerian degeneration (5).
However, these subtypes share common histopathological changes, characterized by neuronal loss, gliosis and the presence of glial cytoplasmic inclusions (GCI) with a-synuclein.5 In MSA-P the degenerative changes predominantly affect the basal ganglia, particularly the putamen seen as hyperintense rim at the putaminal
edge, atrophy and hypointensity of putaminal
body on T2WI while in MSA-C changes predominantly affect infratentorial structures like pons and cerebellum, seen as atrophy and hyperintense signals in pons, cerebellum and middle cerebellar peduncles with pontine hyperintensity (hot cross bun sign) on axial image,4 which was seen in both of our patient's MRI.
A significant association was found between plasma ApoA1 and putaminal
dopamine transporter (DAT) uptake, and it was also confirmed that lower ApoA1 level was related with more severe DAT deficit, even adjusting the confounding factor. Hence, the level of ApoA1 could possibly reflect the severity of motor impairment based on the concept that the level of DAT uptake could reflect motor impairment extent.
An MRI brain scan showed left-sided caudate head and anterior putaminal
Alcohol is a risk factor not for thalamic but for putaminal
hemorrhage:The Akita Stroke Registry.
The aim of this study is to assess the clinical efficacy of minipterional craniotomy in the treatment of hypertensive putaminal
In our patient, the putaminal
lesion could have altered this delicate balance, leading to distorted afferent cortical information.