pyrrolidine


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Related to pyrrolidine: piperazine, Triethylamine

pyrrolidine

(pɪˈrɒlɪˌdiːn)
n
(Elements & Compounds) an almost colourless liquid occurring in tobacco leaves and made commercially by hydrogenating pyrrole. It is a strongly alkaline heterocyclic base with molecules that contain a ring of four carbon atoms and one nitrogen atom. Formula: C4H9N
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Among the observed compounds, L2 with pyrrolidine moiety demonstrated no antioxidant activity; on the contrary, it demonstrated an oxidant activity.
A study has documented that pyrrolidine dithiocarbamate (PDTC), an antioxidant, specifically suppresses NF-kB activation (10).
Spider silk is mainly composed of Glycine, Alanine and large amount of pyrrolidine. These amino acids maintain the moisture of spider silk and prevent it from drying out.
Moreover, SA was used as a simple organocatalyst for the synthesis of diarylmethanones [52], [alpha]-aryl ketones [53], pyrrolidine derivatives [54], 2,3-dihydroquinazolin-4(1H)-ones [55], homoallylic alcohols [56] as well as 3,3'-bis(indolyl)methanes (BIMs) [57].
Butterbur root, prepared to remove all liver-toxic pyrrolidine alkaloids (sold as Petadolex), boasts the most research for allergies and sinus-related conditions (albeit primarily funded by its manufacturers).
(26) reported that TGF-[beta]-induced p38 activation was mediated by the Rac1-regulated generation of ROS in cultured human keratinocytes; nonetheless, the authors observed that DPI and pyrrolidine dithiocarbamate (known as an antioxidant) had no inhibitory effects on the TGF-[beta] induced phosphorylation of Smad2.
All chemicals including Cd[(NO3).sub.2] (Merck Co.), Ammonium Pyrrolidine dithiocarbamate (APDC) (Sigma Aldrich Co.), and Tween 80 (Sigma Aldrich Co.) were of guaranteed laboratory grade reagents.
Dichloromethane, N-methyl pyrrolidine, dimethyl acetamide, and triethylamine were purchased from E-Merck Limited, India.
Those taking pyrrolidine alkaloids should avoid butterbur, but it otherwise can help prevent migraine when dosed at 50-75 mg daily divided up into 2-3 for ages 8-9 years and 100-150 mg daily divided up into 2-3 for ages 10-17 years.
Tanaka et al., "Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1," Surgery, vol.
The pyrrolidine ring of the ligand is represented with a solid line for clarity.
Chen, "Effects of the NF-[kappa]B inhibitor pyrrolidine dithiocarbamate on experimentally induced autoimmune anterior uveitis," Investigative Ophthalmology & Visual Science, vol.