quinacrine


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Related to quinacrine: mepacrine

quin·a·crine

 (kwĭn′ə-krēn′)
n.
A compound, C23H30ClN3O, administered in its hydrochloride form, that was formerly used as an antimalarial and antihelminthic drug and, in some countries, has been used as an agent for the nonsurgical sterilization of women.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

quinacrine

(ˈkwɪnəˌkriːn)
n
1. (Pharmacology) another name for mepacrine
2. (Medicine) quinacrine mustard a nitrogen mustard derived from mepacrine and used as a stain for chromosomes
[C20: from quin(ine) + acr(id) + -ine2]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

quin•a•crine

(ˈkwɪn əˌkrin)

n.
an alkaloid, C23H30ClN3O, used in the treatment of malaria.
[1930–35; quin (ine) + acr (id) + -ine2]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.quinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malariaquinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

quinacrine

n quinacrina, mepacrina (INN)
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
The small molecules are further classified into pentosan polysulfate, quinacrine, amphotericin B, and others.
The correct use of an old malaria drug, "quinacrine," has been one of those discoveries.
It is a dimeric form of the antimalarial drug quinacrine - meaning it has two molecules of quinacrine bound together with a special linker.
A switch to chloroquine, or adding quinacrine, might do the trick, saving at least some patients from having to move on to immunosup pressive therapy, Dr.
Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.
Atabrine: A synthetic antibiotic developed by the German pharmaceutical company Bayer in 1931, Atabrine (the trade name for mepacrine, also called quinacrine) was the first manmade substitute for quinine, the anti-malarial drug of choice at that time.
Rowley, "A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining," Nature, vol.
Croft, Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine, Med.
Tariq, "Protective effect of quinacrine against glycerol-induced acute kidney injury in rats," BMC Nephrology, vol.
Ajarem, "The effects of quinacrine, proglumide, and pentoxifylline on seizure activity, cognitive deficit, and oxidative stress in rat lithium-pilocarpine model of status epilepticus," Oxidative Medicine and Cellular Longevity, vol.
The research in animals has proved that curcumin and quinacrine liposomes not only could enhance apoptosis effects and endocytic effects of C6 glioma stem cells in vitro, but also could increase the survival period of brain glioma-bearing mice and inhibit the growth of gliomas in vivo [32].
Sharma, "Variability in cytogenetic adaptive response of cultured human lymphocytes to mitomycin C, bleomycin, quinacrine dihydrochloride, Co60 y-rays and hyperthermia," Mutagenesis, vol.