The increased plasma concentrations of dextromethorphan after dosing with AXS-09, which contains the chirally pure S-enantiomer of bupropion, are comparable to those achieved with dosing of the company's first generation product candidate AXS-05 which contains racemic
Levobupivacaine is S-enantiomer of racemic
bupivacaine with the similar clinical profile.
It is a racemic
mixture of the dextro & levo stereoisomers.
As an enantiomer of racemic
methadone, REL-1017 has been shown to possess NMDA antagonist properties with virtually no opioid activity at the expected therapeutic doses.
Commercially, ketamine is available as a racemic
mixture and, more recently, as a formulation containing only the S(+)-isomer.
Additionally, it provides access to both racemic
and enantiopure solid-state architectures that can further impact the properties.
Additional studies have evaluated nebulized albuterol, racemic
epinephrine, and corticosteroids.
Initial results from the firm's completed single ascending dose study indicated a potentially therapeutic dose range for d-Methadone without the side effects typically observed with racemic
methadone in opioid naive subjects or with other NMDA inhibitors, such as ketamine.
Chiral Technologies, a leader in enantioselective chromatography, serves pharmaceutical and other life science industries and offers a portfolio of chiral stationary phases and analytical and preparative chiral columns for the separation of racemic
mixtures into single enantiomers.
Her breathing symptoms had been unresponsive to steroids and racemic
Since naturally chiral sources of essential oils are generally more costly and have a greater perceived health benefit than their synthetic counterparts, rapid chiral analysis allows manufacturers to quickly exclude adulterated products containing inexpensive racemic
synthetic materials at the time of purchase.
The second compound, racemic
acid, was discovered in 1819 in the tartaric acid factory of an industrialist named Kestner.