The results demonstrated that both ( R )-albuterol systemic exposure and consequent beta-mediated adverse events were less following cumulative dosing with XOPENEX HFA when compared to cumulative dosing with racemic
albuterol HFA MDI.
DIO-902 is one of two enantiomers contained within racemic
ketoconazole, a marketed drug.
Among the highlights are novel chapters on racemic
separation by capillary electrophoresis and on-line analysis of chiral compounds using mass spectrometry or biosensors.
Levalbuterol was more effective than racemic
albuterol for patients with either airway disease, but levalbuterol was particularly effective in asthma.
synthesis from ephedrine leads to S-(+)-MA, and synthesis from phenylacetone leads to racemic
He was administered racemic
epinephrine, intravenous steroids, and heliox and fitted with bilateral nasal trumpets.
Citalopram, a selective serotonin reuptake inhibitor (SSRI), is actually a racemic
mixture of two enantiomers--molecules that have the same atomic framework but different spatial arrangements that change their interaction with receptors.
We studied two poorly characterized compounds present in the environment, tris-4-(chlorophenyl)methane (Tris-H) and tris4-(chlorophenyl)methanol (Tris-OH), and compared their activities to the organochlorinated pesticide o,p'-DDT (the racemic
mixture and both enantiomers) and a mixture of nonylphenols (NPm; released from polystyrene), which have already been identified to have estrogenic activity.
Levomilnacipran (1S, 2R-milnacipran), an enantiomer of racemic
milnacipran, is protected by a method of use patent that extends through June 2023, without patent term extension.
The initial four cohorts of the Phase 1 study successfully demonstrated a lack of dose limiting side effects with d-Methadone -- even when administered at doses several fold higher than conventionally used with racemic
methadone in opioid naE[macron]ve subjects -- which reinforces the radically different pharmacological profile of the compound," stated Sergio Traversa, chief executive officer of Relmada Therapeutics.
Researchers from the Iowa State University study compared the pharmacokinetics of L-theanine, D-theanine and an ingredient commercially marketed as L-theanine that actually was a racemic
mixture of theanine, a 50:50 D- and L-theanine mixture, also known as racemate.
All other currently available albuterol bronchodilators are 50/50 racemic
mixtures, containing both R- and S-isomers.