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Related to radiolabeling: Isotopic Tracer


tr.v. ra·di·o·la·beled, ra·di·o·la·bel·ing, ra·di·o·la·bels or ra·di·o·la·belled or ra·di·o·la·bel·ling
To tag (a hormone, enzyme, or other substance) with a radioactive tracer.
A radioactive isotope used as a tracer; a radiotracer.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌraɪdɪəʊˈleɪbəl) chem
a radioactive marker, tracer, or label
vb (tr)
to add a radioactive marker, tracer, or label to
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈleɪ bəl)

n., v. -beled, -bel•ing (esp. Brit.) -belled, -bel•ling. n.
1. an inscribed slip of paper, cloth, or other material, for attachment to something to indicate its manufacturer, nature, ownership, destination, etc.
2. a short word or phrase descriptive of a person, group, intellectual movement, etc.
3. a word or phrase indicating that what follows belongs in a particular category or classification, as the word Physics before a dictionary definition.
4. a brand or trademark, esp. of a manufacturer.
5. the manufacturer using such a label.
7. a molding or dripstone over a door or window.
8. a radioactive or heavy isotope incorporated into a molecule for use as a tracer.
9. a narrow horizontal heraldic band with downward extensions.
10. Obs. a strip or narrow piece of anything.
11. to affix a label to; mark with a label.
12. to designate or describe by or on a label.
13. to put in a certain class; classify.
14. to incorporate a radioactive or heavy isotope into (a molecule) in order to make traceable.
[1275–1325; Middle English < Middle French: ribbon, probably < Germanic]
la′bel•er, n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Y-mAbs Therapeutics announced that the Company has entered a development, manufacturing and supply agreement with SpectronRx in South Bend, Indiana, to secure access to clinical and commercial scale radiolabeling capacity for omburtamab.
The leading bioconjugation platform of GeneQuantum will be integrated with the unique advantages of MITRO in radiolabeling and molecular imaging technique to jointly develop next generation radionuclide conjugates for rapid and efficient companion diagnosis and precision target therapy on tumors.
Under the agreement ITM receives an option for a worldwide exclusive license for clinical development and commercialisation of radiolabeled folate derivatives, while Merck KGaA will supply folate precursors for radiolabeling.
Next, changes in ganglioside pattern were evaluated upon differentiation of hTSCs to either osteoblasts or adipocytes, as previously reported [4], by metabolic radiolabeling after 17 and 21 days of cell culturing in either osteogenic (O.D.) or adipogenic (A.D.) medium (Figure 1(a)).
The [Fe.sub.3][O.sub.4]-[Ag.sup.125]I heterostructured radionuclide NPs demonstrate high radiolabeling efficiency and clearly reduced [T.sub.2]-MRI signal intensity.
With its long half-life (>5000 years), its low energy but easily detected beta emission, and its chemical nature present in the backbone of all organic molecules, it has become the mainstay of radiolabeling pharmaceutical drugs since the first tracer study by Melvin Calvin, also at Berkeley.
Among alternative therapeutic radionuclides, rhenium-186 and rhenium-188 have desirable particulate emission characteristics for RIT [7] and are characterized by a very rich chemistry, typical of transition metals, which pave the way for different radiolabeling approaches.
For using [sup.99m]Tc for radiolabeling [Bombesin.sub.(7-14)], which does not have a disulfide bond, 2-hydrazinonicotinamide (HYNIC) is a good chelating agent because its carboxylic acid group reacts with the nitrogen-terminal residue of the peptide.
IBAM NA, with its manufacturing and distribution network, and its expertise in radiolabeling and radiopharmaceutical development, will work collaboratively with Zevacor to produce a range of radionuclides for both research and clinical applications.
Lutetium-177 has radiophysical properties similar to [sup.131]I and radiolabeling chemistry similar to [sup.90]Y.
The other component of the pretargeting system is a small peptide bearing both the fluorescent dye, IRdye800CW, and a linker called DOTA for radiolabeling. Designated as RDC- 018, this new peptide was derived from an earlier peptide, IMP288, that has been used successfully in pretargeting with a number of radioisotopes such as indium-111 (111In),yttrium-90, lutetium-177 and iodine-124.