reagin


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Related to reagin: reign, cardiolipin, VDRL test

re·a·gin

 (rē-ā′jĭn)
n.
1. An antibody found in the blood of individuals having a genetic predisposition to allergies.
2. A substance present in the blood of individuals having a positive serological test for syphilis.


re′a·gin′ic (rē′ə-jĭn′ĭk) adj.
re′a·gin′i·cal·ly adv.

reagin

(ˈrɪədʒɪn)
n
(Biochemistry) immunol a type of antibody that is formed against an allergen and is attached to the cells of a tissue. The antigen–antibody reaction that occurs on subsequent contact with the allergen causes tissue damage, leading to the release of histamine and other substances responsible for an allergic reaction
[C20: from German reagieren to react + -in]

re•a•gin

(riˈeɪ dʒɪn, -gɪn)

n.
1. an antibody formed in response to syphilis in various blood tests for the disease.
2. an antibody found in certain human allergies, as hay fever and asthma.
[1910–15; < German Reagin=reag(ieren) to react + -in -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.reagin - an immunoglobulin E that is formed as an antibody against allergens (such as pollen); attaches to cell membranes causing the release of histamine and other substances responsible for the local inflammation characteristic of an allergy
IgE, immunoglobulin E - one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes
Translations

re·a·gin

n. reagina, anticuerpo usado en el tratamiento de alergias que estimula la producción de histamina.
References in periodicals archive ?
At diagnosis, all three women had a strongly positive Treponema pallidum particle agglutination assay, a high rapid plasma reagin, and a positive syphilis IgM assay.
Laboratory test results were negative for rapid plasma reagin, fluorescent treponemal antibody absorption, tuberculosis (Quantiferon-Gold TB; Quest Diagnostics, https://www.questdiagnostics.com), angiotensin-converting enzyme, rheumatoid factor, antinuclear antibody, and human leukocyte antigen B27.
(11) A quantitative, nontreponemal test such as the rapid plasma reagin (RPR) or the Venereal Disease Research Laboratory (VDRL) will be positive in most infants if exposed through the placenta, but antibodies will disappear in uninfected infants by 6 months of age.
Multivariable logistic regression results demonstrated that gestational age >36 weeks at the time of maternal syphilis diagnosis, higher maternal titers of rapid plasma reagin (RPR) and higher Treponema pallidum particle agglutination assay (TPPA) titers are risk factors for congenital syphilis.
The results of Treponema pallidum particle assay, rapid plasma reagin test, and antibodies to human immunodeficiency virus, hepatitis B virus, and hepatitis C virus were all negative.
At the time of diagnosis, syphilis IgG was also positive with a Rapid Plasma Reagin (RPR) titer of 1: 128, indicating active infection.
The mother did not have a venereal disease research laboratory (VDRL) test or rapid plasma reagin (RPR) test during the pregnancy.
pallidum, the etiological agent of syphilis, produces at least two types of antibodies in human infections: treponemal antibodies that can be detected by fluorescent treponemal antibody absorption (FTA-ABS) and nontreponemal antibody (reagin) that can be detected by RPR antigen card or VDRL test.
Demographic profile, sexual behaviour pattern and clinical features, Rapid plasma reagin test and HIV antibody test results, Treatment given and followup were analysed from the individual STI/RTI patient wise records used in STI clinic.
ELISA for HIV 1 and 2 and rapid plasma reagin (RPR) test were done in all cases.
The patientwas found to have a CD4 count of 101 cells/[mm.sup.3] (22%), an HIV viral load of 2,735,060 copies/mL, a reactive treponemal antibody, and a positive rapid plasma reagin (RPR) titer at 1:64.