receptor modulator


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receptor modulator

n.
A substance that acts on a chemical receptor, usually as an agonist, antagonist, or combination of both: a selective estrogen receptor modulator; a nicotine receptor modulator.
References in periodicals archive ?
Aptinyx announced the presentation of preclinical data on its novel NMDA receptor modulator, NYX-458.
Algiax' lead candidate AP-325 is a small-molecule GABAA receptor modulator in clinical development as a therapy for neuropathic pain.
He is alleged to have taken clomiphene - a selective oestrogen receptor modulator which is prohibited by World Anti-Doping.
It is a next generation and selective sphingosine 1-phosphate receptor modulator developed to treat relapsing forms of multiple sclerosis, including CIS, relapsing remitting disease and active secondary progressive disease, in adults.
According to the company, Mayzent is a next generation, selective sphingosine 1-phosphate receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis (RMS).
For peri- and postmenopausal women with schizophrenia, a selective estrogen receptor modulator, such as raloxifene, may be considered as an adjunctive therapy.
Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells.
Celgene's Phase III SUNBEAM trial, evaluating the efficacy and safety of ozanimod, an investigational oral, selective S1P 1 and 5 receptor modulator, in patients with relapsing multiple sclerosis (RMS), met the primary endpoint in reducing annualized relapse rate (ARR), compared to weekly interferon (IFN) [beta]-1a (Avonex).
The transaction adds Ozanimod, a novel, potential best-in-class, oral, once-daily, selective sphingosine 1-phosphate one and five receptor modulator to Celgene's deep and diverse pipeline of potential disease-altering medicines and investigational compounds.
Vaginal lubricants and moisturizers, vaginal estrogen, and ospemifene, a recently approved oral drug that is a selective estrogen receptor modulator (SERM), can all be used to treat it.
The FDA announced the approval last month, less than 2 months after the FDA's Reproductive Health Drugs Advisory Committee unanimously agreed that the selective progesterone receptor modulator was an effective emergency contraceptive with an acceptable safety profile, when used within 5 days of unprotected intercourse or a known or suspected contraceptive failure, which are the approved indication.

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