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 (rē-kŏm′bə-nās′, -nāz′)
An enzyme that catalyzes the exchange of short pieces of DNA between two long DNA strands, particularly the exchange of homologous regions between the paired maternal and paternal chromosomes.
References in periodicals archive ?
Here, mice were injected with a retroviral vector carrying PDGF, Cre recombinase, and a reporter.
Multicopy transgenes are not suitable for conditional knockout; even if transgenes are floxed (loxP sequence from bacteriophage P1 is inserted and can be recombined between two loxP sites by Cre recombinase from bacteriophage P1), only some of the copies are removed by recombinases, resulting in the failure of knockout.
Excision of selectable genes from transgenic goat cells by a protein transducible TAT-Cre recombinase.
MCK-Cre recombinase, which also expressed in a low level in cardiac muscle, was commonly used in creating skeletal muscle conditional activation or inactivation of genes in mice.
According to the company, unlike competing technologies, VanGogh exhibits >90% efficiency, eliminates unexcised cells, and does not require additional transfection or transduction of cells with a recombinase or transposase.
Site-specific inversion require the presence of specific recombinase enzymes which invert particular DNA fragment resulting in ON to OFF or OFF to ON switching of gene placed within the invertable segment of DNA or next to the switch.
A reverse transcription recombinase polymerase amplification (RT-RPA) assay was able to quickly and effectively identify chikungunya virus (CHIKV), according to a study published in PLOS Neglected Tropical Diseases.
Notably, TbBRC2 interacts with the main recombinase TbRAD51 through BRC repeats.
CTCs in one of the subgroups showed increased expression levels of RAD51 recombinase (RAD51).
Flipping or deleting those sites alters what will happen to the DNA if a second or third recombinase is later activated.
Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples," Journal of Molecular Diagnostics, vol.
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