recombinase


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re·com·bi·nase

 (rē-kŏm′bə-nās′, -nāz′)
n.
An enzyme that catalyzes the exchange of short pieces of DNA between two long DNA strands, particularly the exchange of homologous regions between the paired maternal and paternal chromosomes.
References in periodicals archive ?
Here, mice were injected with a retroviral vector carrying PDGF, Cre recombinase, and a reporter.
The Updated World Health Organization Glioma Classification: Cellular and Molecular Origins of Adult Infiltrating Gliomas
Multicopy transgenes are not suitable for conditional knockout; even if transgenes are floxed (loxP sequence from bacteriophage P1 is inserted and can be recombined between two loxP sites by Cre recombinase from bacteriophage P1), only some of the copies are removed by recombinases, resulting in the failure of knockout.
Comprehensive functional genomics using Caenorhabditis elegans as a model organism
Excision of selectable genes from transgenic goat cells by a protein transducible TAT-Cre recombinase.
Human lactoferrin efficiently targeted into caprine beta-lactoglobulin locus with transcription activator-like effector nucleases
MCK-Cre recombinase, which also expressed in a low level in cardiac muscle, was commonly used in creating skeletal muscle conditional activation or inactivation of genes in mice.
A Transcriptomic Analysis of Physiological Significance of Hypoxia-inducible Factor-1a in Myogenesis and Carbohydrate Metabolism of Genioglossus in Mice
According to the company, unlike competing technologies, VanGogh exhibits >90% efficiency, eliminates unexcised cells, and does not require additional transfection or transduction of cells with a recombinase or transposase.
Progenitor Develops VanGogh Self-Excising Cassette, Rodin Gene Switching Platforms for 'Off-the-Shelf' Cellular Immunotherapy Development
Site-specific inversion require the presence of specific recombinase enzymes which invert particular DNA fragment resulting in ON to OFF or OFF to ON switching of gene placed within the invertable segment of DNA or next to the switch.
An overview on phase variation, mechanisms and roles in bacterial adaptation
The first gene encodes a protein that suppresses the second gene, a recombinase gene.
Genetic use restriction technologies and possible applications in the integrated pest management/Tecnologias geneticas de restricao de uso e possiveis aplicacoes no manejo integrado de pragas
A reverse transcription recombinase polymerase amplification (RT-RPA) assay was able to quickly and effectively identify chikungunya virus (CHIKV), according to a study published in PLOS Neglected Tropical Diseases.
New chikungunya diagnostic assay proves quick, effective
Notably, TbBRC2 interacts with the main recombinase TbRAD51 through BRC repeats.
Aptamers as a promising approach for the control of parasitic diseases
CTCs in one of the subgroups showed increased expression levels of RAD51 recombinase (RAD51).
Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells
Flipping or deleting those sites alters what will happen to the DNA if a second or third recombinase is later activated.
Scientists Program Cells to Remember & Respond to Series of Stimuli
Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples," Journal of Molecular Diagnostics, vol.
A systematic review of point of care testing for Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis
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