refractoriness


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re·frac·to·ry

 (rĭ-frăk′tə-rē)
adj.
1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior.
2. Difficult to melt or work; resistant to heat: a refractory material such as silica.
3. Resistant to treatment: a refractory case of acne.
n. pl. re·frac·to·ries
One that is refractory, especially a material that has a high melting point.

[Alteration (influenced by adjectives in -ory) of obsolete refractary, from Latin refrāctārius, from refrāctus, past participle of refringere, to break up; see refract.]

re·frac′to·ri·ly adv.
re·frac′to·ri·ness n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.refractoriness - the trait of being unmanageablerefractoriness - the trait of being unmanageable  
intractability, intractableness - the trait of being hard to influence or control

refractoriness

noun
Translations

refractoriness

[rɪˈfræktərɪnɪs] Nobstinación f

refractoriness

n
(of person)Eigensinn m, → störrische Art
(Med) → Hartnäckigkeit f
(Chem, Miner) → Hitzebeständigkeit f
References in periodicals archive ?
LightIntegra's efforts to minimize platelet refractoriness have resulted in the introduction of ThromboLUX, a rapid in-vitro test that assesses platelet activation status.
The 5D mnemonic has also been developed to list common biomedical causes of refractoriness in diabetes management3.
A slightly slower recovery of SR [Ca.sup.2+] release was observed in the SHS group following 12 wk of exposure, potentially indicating slower recovery of RyRs from refractoriness. Although this difference was not statistically significant, this trend only appeared following 12 wk of exposure and is consistent with the increasing severity of [Ca.sup.2+] alternans at 12 wk in the SHS group.
4) exhibited regular seminiferous tubules with a lack of successive stages of spermatogenesis and the absence of spermatozoa in the lumen of somniferous tubules marking thus, gonads regression and a refractoriness period.
THE unilateral inception/operation of Kishanganga Dam by the Indian prime minister in the Indian occupied Kashmir is reflective of Indian refractoriness regarding expanding its water reservoirs without taking Pakistan into confidence.
However, despite refractoriness to antipsychotic treatment of negative symptoms (Leucht, Corves, Arbter, Engel, Li, & Davis, 2009) and the pessimism that surrounds them, different psychological approaches have shown some effectiveness, as Cognitive Behavioral Therapy (Rector, Seeman, & Segal, 2003), Cognitive Remediation Therapy (Gharaeipour & Scott, 2012) and Integrated Psychological Therapy (Roder, Mueller, & Schmidt, 2011).
Given the patient's refractoriness to imatinib, an alternative TKI was used, which fortunately to date has not produced recurrent PH symptoms in the patient even though there are reported cases of bosutinib-associated PH and though the putative causative pathway may be invoked by both drugs.
CCA accounts for approximately 3% of all gastrointestinal malignancies [1, 2] and has a high mortality rate, given its late diagnosis and refractoriness to therapy [3].
demonstrated that pregnancy normally leads to acquired vascular refractoriness to Angiotensin II (ATII) [19].
In isolated canine, arterially perfused right atrial preparations, Wenxin Keli significantly prolonged effective refractory period (ERP) and induced postrepolarization refractoriness (PRR) despite abbreviating the action potential duration in an atrial-selective manner.
Kaolin has wide application in industry due to its whiteness, inertness to chemical agents, electric insulator properties, mold ability, and ease of extrusion; also, it resists high temperatures, is nontoxic, and has high refractoriness. In Mexico, there are several kaolin deposits, and the most important ones are located in the States of Guanajuato, Hidalgo, and Veracruz [2].
The final blood culture became negative, but finally he was died due to refractoriness of leukemia and poor response to chemotherapy 8 weeks after admission.