Inappropriate Expression of Hepcidin is associated with Iron Refractory Anemia
: Implications for the Anemia of Chronic Disease.
Clonal SA is related to various MDS subcategories including refractory anemia
with ring sideroblasts (RARS), refractory cytopenias with multilineage dysplasia with ring sideroblasts (RCMD-RS) and refractory anemia
with ring sideroblasts and thrombocytosis (RARS-T).
14 patients had refractory anemia
(RA), six had an isolated deletion of the long arm of chromosome 5 (del(5q)), 5 had refractory anemia
with ring sideroblasts (RARS), 17 had refractory cytopenia with multilineage dysplasia (RCMD), 15 had refractory anemia
with excess blasts 1 (RAEB-1), and 19 had RAEB-2.
was present in 66.6% patients in NDCD group and 41.1% patients in CCD group.
Helicobacter pylori gastric infection and sideropenic refractory anemia
. J Pediatr Gastroenterol Nutr 1993;17(2):2257.
Correia Jr., "Isochromosome 14q in refractory anemia
," Cancer Genetics and Cytogenetics, vol.
(1) The 88 patient population consisted of 58 men (65.9%) and 30 women (34.1%) (median age, 62 years; range, 22-87 years); 10 patients (11.4%) had refractory cytopenia with unilineage dysplasia (RCUD), 17 (19.3%) had refractory cytopenia with multilineage dysplasia (RCMD), 28 (31.8%) had refractory anemia
with excess of blasts-1 (RAEB-1), 25 (28.4%) had RAEB-2, 1 (1.1%) had refractory anemia
with ring sideroblasts, and 7 (8.0%) had MDS-unclassifiable.
The different malignancies that caused pancytopenia in their study were AML (62.5%), acute lymphocytic leukemia (28.12%), plasma cell myeloma (3.12%), non-Hodgkin's lymphoma (3.12%), and myelodysplastic syndrome (i.e., refractory anemia
with excess of blasts, 2 (3.12%)].
[USPRwire, Tue Nov 03 2015] GlobalData's clinical trial report, "Refractory Anemia
With Excess Blasts Global Clinical Trials Review, H2, 2015" provides an overview of Refractory Anemia
With Excess Blasts clinical trials scenario.
GlobalData's clinical trial report, "Refractory Anemia
Global Clinical Trials Review, H2, 2015" provides an overview of Refractory Anemia
clinical trials scenario.
The findings are consistent with a highgrade myelodysplastic syndrome, best classified as refractory anemia
with excess blasts-2 (RAEB-2) on the basis of the blast count and presence of myelodysplasia.
Siddappa and colleagues presented a rare case of renal hemosiderosis appearing with renal failure due to repeated blood transfusion (about 2 per month) over past 2 years for chronic refractory anemia
.[sup.25] Three cases of paroxysmal nocturnal hemoglobinuria with renal hemosiderosis and renal failure were reported by Nair and colleagues.[sup.10] Most patients with renal hemosiderosis also have renal failure.