The blood concentration of amiodarone can reach the peak at the 4th to 6th h, and a low blood concentration can still be detected even half a year after withdrawal.14,15 Its main pharmacological function is to eliminate re-entrant excitation, inhibit the rapid sodium ion internal flow of the atrial and myocardial conduction fibers and reducing sinus-node self-activity through prolonging the action potential and effective refractory period
of the myocardial tissue of patients.16 In addition, amiodarone has four kinds of antiarrhythmic functions.
When two stimuli (S1 and S2) are presented in rapid succession to which participants are asked to make separate speed responses, reaction times to the second stimulus (RT2) show a significant increase with decreasing stimulus-onset asynchrony (SOA) between the two stimuli. This phenomenon is termed as the psychological refractory period
(PRP) effect. The dominant theory with regard to the mechanisms underlying the PRP effect is the response-selection bottleneck model proposed by Welford and Pashler:,,, the central response-selection stage constitutes a single-channel bottleneck, and thus can be only executed serially, whereas the other stages, for example, perceptual and motor stages, can be performed in parallel with concurrent processes of another task.
ludens males from the genetic sexual strain (GSS)Tapachula-7 (Tap-7) in inducing the refractory period
of wild females, by varying pupal age at which irradiation took place, and male sexual experience.
Studies have proven that PSVT due to AVNRT in older subjects is often related to an atrioventricular conduction abnormality, the longer AVN conduction intervals and refractory period
explaining the late development of AVNRT .
Furthermore, the model could be cracked repeatedly without hindrance by any refractory period
between sequential iterations.
If the accumulated weighted input becomes positive and the neuron is not in its refractory period
, the neuron n outputs a spike after a delay time [D.sub.nk] as the kth firing.
The absolute refractory period
was recorded using paired shock technique by calculating M wave (M1 and M2) at two supramaximal stimuli (S1 and S2) with an initial time delay between them at 8.0 ms.
Once the hypothalamic-pituitary axis has produced a pulse of GH, there is a refractory period
where stimulation from other sources will not elicit a GH response.
Stimulation of GP can convert the firing from PVs into AF in dogs and in humans [11-13], then promote maintenance of AF due to markedly reduced atrial effective refractory period
(ERP), widen the window of vulnerability (WOV), and increase gradient differences in ERP and WOV towards GP, which serve as heterogeneous substrate caused by GP hyperactivity .
Atrial fibrillation (AF) is known to induce atrial electrical remodeling (AER), which includes shortening, maladaptation, and increased dispersion of atrial effective refractory period
(AERP) as well as decreased atrial conduction velocity (1, 2).
He said women do not have such a strong refractory period
- which is a recovery phase when the body calms down - and may be wondering why their partners have lost all interest when they just want more.