releasing factor


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Related to releasing factor: corticotropin releasing factor, growth hormone releasing factor

re·leas·ing factor

(rĭ-lē′sĭng)
n.
Any of several hormones secreted by the hypothalamus that stimulate the anterior part of the pituitary gland to release certain hormones.

releas′ing fac`tor


n.
a substance usu. of hypothalamic origin that triggers the release of a hormone from an endocrine gland.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.releasing factor - a substance produced by the hypothalamus that is capable of accelerating the secretion of a given hormone by the anterior pituitary gland
factor - anything that contributes causally to a result; "a number of factors determined the outcome"
GHRF, growth hormone-releasing factor - a releasing factor that accelerates the secretion of growth hormone by the anterior pituitary body
2.releasing factor - any of several hormones produced in the hypothalamus and carried by a vein to the anterior pituitary gland where they stimulate the release of anterior pituitary hormones; each of these hormones causes the anterior pituitary to secrete a specific hormone
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
References in periodicals archive ?
NASDAQ: NBIX) announced today that NBI-77860, a proprietary corticotropin releasing factor 1 (CRF) receptor antagonist, has been granted orphan drug status by the United States Food and Drug Administration (FDA) for the treatment of congenital adrenal hyperplasia (CAH) a disease that affects approximately 20,000-30,000 people in the United States.
Corticotropin releasing factor (CRF): Studies in alcohol preferring and non-preferring rats.
Corticotropin releasing factor (CRF), a neuropeptide, is known to be related to these physiological functions and neurological disorders.
Circulating growth hormone releasing factor concentrations in normal subjects and patients with acromegaly.
The Phase 2 trial, which involved 150 patients experiencing a major depressive episode, found no benefit for patients treated with the experimental drug, a corticotropin releasing factor (CRF1) receptor antagonist called GSK561679.
Central regulation of gastric emptying of solid nutrient meals by corticotropin releasing factor.
Their topics include the life cycle of depression, considerations of cognitive, psychodynamic, and cognitive-behavioral theories, the role of development and its implications in childhood and adolescent depression, developments in psychodynamic development psychopathology such as complex developmental pathways, and the integration of psychology and neurobiology in such treatment tools as corticotropin releasing factor.
The company also confirmed that it has requested a meeting with the Food and Drug Administration (FDA) in the United States to discuss advancing ThGRF (TH9507), an analogue of growth hormone releasing factor, into late-stage development.
The Salk Institute for Biological Studies (La Jolla, CA) has patented a G-protein-coupled receptor proteins (CRF-R) characterized by having sufficient binding affinity for corticotropin releasing factor (CRF) such that concentrations of 10 nM of CRF occupy 50% of the binding sites of said receptor protein.
Stress increases Corticotropin Releasing Factor (CRF) and Proopiomelanocortin (POCM) release.
Note: CRF - corticotropin releasing factor; TRH - thyrotropin releasing hormone; GHRF - growth hormone releasing factor, SOM-somatostatin; ACTH-adrenocorticotropin; GH - growth hormone; LH - leutinizing hormones; FSH - follicle-stimulating hormone; PRL - prolactin; NK - natural killer cell; IFN - interferon; IL - interleukin
NASDAQ: NBIX) announced today that NBI-77860, a proprietary corticotropin releasing factor 1 (CRF) receptor antagonist, has entered clinical trials for the treatment of classic congenital adrenal hyperplasia (CAH) a disease that affects approximately 20,000-30,000 people in the United States.