While renal denervation is gaining popularity with leading multi-nationals developing new devices and initiating new clinical trials in and outside the USA, the market still lacks a solution that addresses the basic limitations of the current technology, including difficulty in accessing the renal artery
, inability to predict lesion formation and the need for multiple catheters per procedure.
aneurysms (RAAs) are a rare occurrence, with an incidence of about 1% (1, 2).
Paradise, which has CE mark, uses 6Fr or 5Fr catheters for intravascular denervation of the renal nerves by combining water-based cooling of the renal artery
and high intensity ultrasound energy for circumferential renal nerve ablation.
7,8) The most sensitive and specific imaging test for renal infarction is renal artery
Non-contrast enhanced MR angiography (MRA) techniques have attracted interest in the medical community for diagnosing renal artery
stenosis, as it eliminates the need for gadolinium-based contrast agents used with CT angiography (CTA).
The results from the multi-center trial demonstrated the high sensitivity, specificity and diagnostic accuracy of Time-SLIP while also showing no statistical differences between non-contrast MRA and CTA in terms of their ability to visualize renal artery
In patients with atherosclerotic renal artery
stenoses and hypertension, clinical outcomes were not improved by the use of stents.
The announcement from Medtronic in January has apparently brought down the curtain on the much-heralded approach to the treatment of refractory hypertension using radiofrequency renal artery
sympathetic nerve ablation (RASNA) applied through the tip of the Symplicity catheter.
The renal artery
ablation procedure is undertaken using a special catheter connected to a generator which delivers low power radiofrequency energy, and applies this to each renal artery
at 4-6 points to ensure the nerve is severed.
Renal medicine and other physicians from the UK provide 13 chapters covering diagnostic tests; acute kidney injury; the prevalence, detection, and evaluation of chronic kidney disease; pre-dialysis clinics for end-stage renal disease; anemia management; urinary tract infections, renal stones, renal cysts, tumors, and pregnancy in chronic kidney disease; adult nephrotic syndrome; renal artery
stenosis; palliative care; dialysis and renal transplantation, including issues with children; and the organization of services for patients.
At least one hypertension expert should be involved in treatment and screening and the intervention should be performed by interventional cardiologists or angiologists with training in percutaneous renal artery
METHODS AND RESULTS: Four groups of pigs were studied after 12 weeks of a normal diet (n = 9), a 2% HC diet (n = 9), HT (achieved by unilateral renal artery
stenosis, n = 8), or HC+HT (n = 6).