renin


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re·nin

 (rē′nĭn, rĕn′ĭn)
n.
An enzyme released by the kidneys that cleaves a plasma protein to produce an inactive form of angiotensin which is then converted to an active form that raises blood pressure.

[Latin rēnēs, kidneys + -in.]

renin

(ˈriːnɪn)
n
(Biochemistry) a proteolytic enzyme secreted by the kidneys, which plays an important part in the maintenance of blood pressure
[C20: from reni- + -in]

re•nin

(ˈri nɪn)

n.
a proteolytic enzyme secreted by the kidneys that is involved in the release of angiotensin.
[< German Renin (1897) = Latin rēn(ēs) kidneys + German -in -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.renin - a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
Translations

re·nin

[MIM*179820]
n. renina, enzima segregada por el riñón que interviene en la regulación de la presión arterial.
References in periodicals archive ?
Amacimiz, sol ventrikul sistolik fonksiyonu normal olan farkli AF hastalarinda, plazma renin aktivitesi (PRA) ve N-terminal pro-B-tipi natriuretik peptit (NT-proBNP) duzeylerini degerlendirmektir.
Rotimi Aluko, of the department of human nutritional sciences, says pea peptides provide relief for hypertension in two ways: they block renin, the root cause of increased blood pressure found early on in the biochemical pathway, and they reduce kidney disease progression.
Beta-1 receptors also exist in the kidneys, where the action of the beta blockers decreases the release of renin; this activity also decreases the blood pressure.
Rasilez combats the problem by directly blocking renin, a hormone that increases blood pressure.
The FDA issued the approval for Tekturna as the first in a new class of drugs called direct renin inhibitors.
Ten biomarkers in 3209 participants attending a routine examination cycle of the Framingham Heart Study: the levels of C-reactive protein, B-type natriuretic peptide, N-terminal pro-atrial natriuretic peptide, aldosterone, renin, fibrinogen, D-dimer, plasminogen-activator inhibitor type 1, and homocysteine; and the urinary albumin-to-creatinine ratio.
For instance, studies suggest that part of the reason for the disparities in rates of heart disease may be differences in how African Americans process salt and use renin, an enzyme secreted by the kidneys, resulting in high rates of hypertension.
When renal ischemia occurs due to hypovolemia, decreased cardiac contractility, or renal artery stenosis, among other conditions, the kidney produces the proteolytic enzyme, renin, from the granular cells of the juxtaglomerular apparatus (JGA).
One way to find out what's best for a patient is to assess the function of the renin system.
Doctors already have a biochemical test for renin, one of the key chemicals regulating blood pressure.
Objective: To analyse the spectrum of renin angiotensin aldosterone system disorders in young hypertensive patients in hospital settings.
7.The peptide hormone renin is secreted by which organ of the body?