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A genetic element that undergoes replication as an autonomous unit.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Genetics) genetics a region of a DNA molecule that is replicated from a single origin
[C20: from replic(ation) + -on]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈrɛp lɪˌkɒn)

any genetic element that can regulate and effect its own replication from initiation to completion.
[< French (1963), shortened form of réplication; see -on1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Arcturus' versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, replicon RNA, antisense RNA, microRNA, DNA, and gene editing therapeutics.
By mapping read data against each individual replicon, we noted that isolates E and 20 do not carry the plasmid, which appears to be a stochastic event because the SNP phylogeny indicates that these isolates are not derived from a common ancestor.
Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.
Morphine enhances hepatitis C virus (HCV) replicon expression.
Hepatitis C genotype 1b cell-based replicon assays using combinations of CC-31244 with other classes of hepatitis C drugs showed additive and synergistic effects of CC-31244, providing important information for ultra-short therapy cocktail regimens.
Carattoli, "Replicon sequence typing of IncF plasmids carrying virulence and resistance determinants," Journal of Antimicrobial Chemotherapy, vol.
However, it is sometimes regarded as a RAS [10, 51], despite conferring only 1.2 fold change in resistance in in vitro studies using the 1a replicon system [39].
Toward this goal, next-generation encephalitic alphavirus vaccine candidates, including live-attenuated, inactivated, Sindbis virus-based chimeric, virus replicon particle, virus-like particle, DNA, and virus-vectored vaccines, are all currently at various stages of development [20-22].
(11-14) Moreover, plasmids were searched following the PCR-based replicon typing (PBRT) scheme targeting replicons of the major incompatibility groups (Inc) harboring/disseminating antibiotic resistance genes in Enterobacteriaceae.
Bartenschlager, The Hepatitis C Virus Replicon System: from Basic Research to Clinical Application.
For the first, it allows to determine the properties and functions of the genes carried by its replicon, which will provide new data on the species concerned.