'We have previously shown that connective tissue cells can be reprogrammed
into dendritic cells using only three proteins.
ROCHESTER, Minn., February 12, 2019 -- Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed
to pluripotent stem cells by exposure to a complex set of genetic cocktails.
(28),(29) In addition, the forced expression of the transcription factor MyoD induces myogenic differentiation in many cell types, suggesting that specifically differentiated somatic cells can also be reprogrammed
into other types of differentiated cells.
Likewise, we observed an increase in reprogramming efficiency, with frequent areas of spontaneous contraction and enhanced expression of cardiac contractile proteins when we reprogrammed
MEFs with GMT and A83-01 cells (Figure 1).
Probably because of this, PGCs are easily reprogrammed
toward pluripotent embryonic germ cells (EGCs) when cultured with basic fibroblast growth factor (bFGF) or trichostatin A (TSA) [7-9].
TEHRAN (FNA)- Researchers established for the first time that skin cells from diabetic foot ulcers can be reprogrammed
to acquire properties of embryonic-like cells.
They have discovered a new class of cells, generated from mouse tissue, that can be reprogrammed
to become almost any cell in the body.
cells that do not pass through the pluripotent state may not be tumorigenic and may serve as a potential alternative to iPSCs for generating patient- and/or disease-specific neurons.
" scar-forming fibroblast cells into the building blocks of beating heart muscle by injecting them with a cocktail of five genes.
Washington, Feb 1 ( ANI ): A genetically reprogrammed
Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, scientists at the University of Bologna have found.
Gurdon of the University of Cambridge and Shinya Yamanaka of Kyoto University for the discovery that mature cells can be reprogrammed
to become pluripotent.