The surface erosion, ulceration, fold involvement, wall deformity, pitting, and non-lifting patterns are important characteristics of a lesion to determine the local resectability
. For a gastric lesion, which seems removable with ESD in experienced hands, conventional biopsy may complicate the success of ESD by creating fibrosis in the body of the lesion and may disrupt its integrity (Statement 3).
Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability
of hepatic colorectal metastases.
Abdominal and chest CT reveal the possibility of resectability
and identify pulmonary metastasis.
Patients with 'intermediate-risk' group tumors which are not amenable for primary resection receive chemotherapy to halt rapid tumor progression, treat life-threatening symptoms, or improve tumor resectability
. Chemotherapy (4-8 cycles) for debulking and metastatic remission, followed by surgery aiming at maximum safe resection (residual tumor need not cause concern), is the recommended approach.
The earlier the disease is diagnosed and its resectability
established, the better is the prognosis.
An early diagnosis that allows for appropriate therapy and surgical resectability
remains one of the most important prognostic factors.
Patients who required defunctioning colostomy prior to CMT were analysed for indication of stoma, potential resectability
of tumour prior to CMT, response to treatment and stoma closure rate.
Tumour growth was more rapid and patients presented with larger tumour burdens, resulting in resectability
rates as low as 1%.
The 2015 National Comprehensive Cancer Network guidelines describe the current criteria used to assess for tumor resectability
. (4) Important features to include in the radiology report include the size and location of the mass, the presence of pancreatic or biliary ductal dilation, degree of arterial and venous contact, the presence of venous thrombus, variant vascular anatomy, tumor invasion of local structures, and the presence of metastatic disease.
In our series this may be reflective of inadequate surgical technique as stage and surgical resectability
seem to be the most predictive thus far.
All patients underwent cross-sectional contrast-enhanced computed tomography or magnetic resonance imaging of the chest, abdomen, and pelvis to assess the resectability
of the tumor and to plan the hepatectomy.