retinitis pigmentosa


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retinitis pig·men·to·sa

 (pĭg′mĕn-tō′sə, -mən-)
n.
A hereditary degenerative disease of the retina, characterized by night blindness, pigmentary changes within the retina, and eventual loss of vision.

[New Latin pigmentōsa, feminine of pigmentōsus, pigmented.]

retinitis pigmentosa

(ˌpɪɡmənˈtəʊsə)
n
(Medicine) a degenerative hereditary disease of the human eye, characterized by pigmentary changes in the retina, night blindness, and eventual loss of vision
[C19: pigmentosa, feminine of Latin pigmentosus]

retini′tis pig•men•to′sa

(ˌpɪg mɛnˈtoʊ sə, -mən-)
n.
degeneration of the retina manifested by night blindness and gradual loss of peripheral vision, eventually resulting in tunnel vision or total blindness.
[1860–65; < New Latin: pigmentary retinitis. See pigment, -ose1]

retinitis pigmentosa

Degeneration of the light-sensitive cells of the retina.
References in periodicals archive ?
QR-1123 is a first-in-class investigational oligonucleotide designed to address the underlying cause of the vision loss associated with autosomal dominant retinitis pigmentosa (adRP) due to the P23H mutation in the rhodopsin (RHO) gene.
In the study, detailed in the Proceedings of the National Academy of Sciences, the team used a viral vector to express a light sensitive protein, melanopsin, in the residual retinal cells in mice which were blind from retinitis pigmentosa.
Usher syndrome type 2a is an autosomal recessive genetic condition characterised by hearing loss from birth and progressive vision loss, due to retinitis pigmentosa, that begins in adolescence or adulthood.
The other initiative is Medical and Research programme which is serving as a focal point for dissemination of information to affected families, specialists and the society at large about genetically inherited eye diseases such as Retinitis Pigmentosa (RP) and Allied Retinal Dystrophies.
Ophthalmology company Bascom Palmer Eye Institute stated on Wednesday that a Puerto Rican patient with X-linked retinitis pigmentosa (XLRP) is undergoing the innovative gene therapy procedure at the University of Miami Miller School of Medicine.
Berson, M.D., from Harvard Medical School in Boston, and colleagues conducted a nonrandomized comparison study involving children with retinitis pigmentosa taking or not taking vitamin A supplementation (55 and 25, respectively).
"We expect to demonstrate that we can restore vision in patients who have lost their sight due to all forms of retinitis pigmentosa and potentially to dry macular degeneration," Dr Gilly said.
Clinical findings and common symptoms in retinitis pigmentosa. Am J Ophthalmol.
To this day, molecular research has found and identified a huge number of mutations in genes associated with retinitis pigmentosa. However, molecular research suggests that different mutations involved in RP largely share a common functional or structural abnormality [9, 10].
The widespread custom of consanguineous marriages in South Asian countries puts the population at risk for autosomal recessive disorders including retinitis pigmentosa.