retinoblastoma


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ret·i·no·blas·to·ma

 (rĕt′n-ō-blă-stō′mə)
n. pl. ret·i·no·blas·to·mas or ret·i·no·blas·to·ma·ta (-mə-tə)
A hereditary malignant tumor of the retina, transmitted as a dominant trait and occurring chiefly among infants.

retinoblastoma

(ˌrɛtɪnəʊˌblæsˈtəʊmə)
n
a cancerous tumour of the retina which normally occurs in children under five years old

ret•ino•blas•to•ma

(ˌrɛt n oʊ blæˈstoʊ mə)

n., pl. -mas, -ma•ta (-mə tə)
an inheritable tumor of the eye.
[1920–25]

retinoblastoma

a common childhood malignancy of the eye that develops from retinal cells.
See also: Cancer

retinoblastoma

Cancer of the retina.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.retinoblastoma - malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
malignant neoplasm, malignant tumor, metastatic tumor - a tumor that is malignant and tends to spread to other parts of the body
Translations

ret·i·no·blas·to·ma

[MIM*180200, 180201, 180202]
n. retinoblastoma, tumor maligno de la retina gen. hereditario.

retinoblastoma

n retinoblastoma m
References in periodicals archive ?
WEDNESDAY, May 2, 2018 (HealthDay News) -- Oculo-visual problems among adult retinoblastoma survivors are associated with patient-reported vision-targeted health-related quality of life (HRQoL), according to a study published online April 26 in JAMA Ophthalmology.
Retinoblastoma is the most common malignant intraocular tumor in childhood, with a prevalence of approximately 1 in 20,000/ Treatment methods for retinoblastoma include systemic chemotherapy, local chemotherapy, photocoagulation, cryotherapy, thermotherapy, brachytherapy, external radiotherapy, enucleation and exenteration.
Retinoblastoma is a pediatric cancer of the retina most often caused by inactivation of the retinoblastoma tumor suppressor gene.
In our case-control study, maternal age shows positive linear trends (age groups are taken to be continuous) for 2 childhood cancer groups: osteosarcoma (p=0.019) and retinoblastoma (p=0.04); however after adjustment for covariates (paternal age, number of siblings, and level of parental education), maternal age only indicated a positive linear trend for retinoblastoma (p=0.037).
Retinoblastoma is the most common malignant intraocular tumor of childhood, most commonly observed between the ages of one and three years (4).
Retinoblastoma is the commonest tumor (43% overall and 87% among children).
IHC study of retinoblastoma showed NSE, S 100 and Synaptophysin positivity.
Retinoblastoma (Rb) is the most common childhood intraocular tumor, and 90% of the cases are diagnosed before the age of 5 years worldwide [1, 2].
Retinoblastoma protein (pRB) was the first identified tumor suppressor that negatively regulates the G0/G1 to S phase transition of the cell cycle [1-4].

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