feedback inhibition

(redirected from retroinhibition)
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feedback inhibition

n.
A cellular control mechanism in which an enzyme that catalyzes the production of a particular substance in the cell is inhibited when that substance has accumulated to a certain level, thereby balancing the amount provided with the amount needed.
References in periodicals archive ?
A comprehensive explanation would also take into account the retroinhibition of 11-HSD-2 activity by increased serum E that Rusvai and Fejs-Toth [42] and Stewart et al.
Progressive 11-HSD-2 overload could account for the positive correlation between the F/E ratio and the F concentration, whereas retroinhibition of 11-HSD-2 by E might play a role in the negative correlation between F/E and E.