Therefore, the wisest way to minimize the chances that your cat can be afflicted with vaccine-associated sarcoma--while still adequately protected against life-threatening infections--is to make sure that the animal receives the initial set of core vaccines, but then to limit the number of revaccinations that it receives during its lifetime to those that are necessary.
Another revaccination should be administered one year after the initial vaccination, and booster shots should be given every three years thereafter.
multiple revaccinations because of insufficient data regarding clinical benefit, particularly the degree and duration of protection, and safety.
ACIP recommendations for revaccination with PPSV23 among the adult patient groups at greatest risk for IPD (i.e., persons with functional or anatomic asplenia and persons with immunocompromising conditions) remain unchanged (2).
This week the clinics are sending letters to patients recommending revaccinations
. There will be no charge to the patients.
With vaccine coverage between 64% and 74%, 1 death was prevented for every estimated 302 vaccinations, and 1 death was prevented for every estimated 195 revaccinations
, the investigators said (JAMA 2004;292:2089-95).
"We anticipate adverse events in revaccinations
may be higher than before."
Also, as immunity of past vaccines wanes over decades, revaccinations
would be needed.
Death is rare after vaccinia vaccination, with approximately 1 to 2 deaths per million primary vaccinations and 0.1 death per million revaccinations
. Death is most often the result of postvaccinial encephalitis or progressive vaccinia.
(3) Data from relatively small studies describe levels (titers) of vaccine-induced neutralizing antibodies for up to 50 years after vaccination or revaccination