The pills can cause muscle aches and rhabdomyolysis
, when muscle is broken down.
The most serious risks associated with YONDELIS are neutropenic sepsis (severe infections due to decreased white blood cells), rhabdomyolysis
(severe muscle problems), cardiomyopathy (heart muscle problems, including heart failure), hepatotoxicity (liver problems, including liver failure), anaphylaxis, and extravasation (leakage of YONDELIS out of the vein during infusion) leading to tissue necrosis (tissue cell damage or death) and embryofetal toxicity.
Despite their efficacy, common side effects including creatine phosphokinase (CPK) elevations, fatigue, weakness, myalgia, liver transaminases increase and rhabdomyolysis
contribute to low adherence to treatment.
is characterized by skeletal muscle breakdown.
A closely related amphetamine, known as Ecstasy, initially used as an appetite suppressant, rapidly became a recreational drug used in dancing clubs and was found to cause hyperthermia, dehydration and rhabdomyolysis
, and an increased risk of acute renal failure.
Case reports have documented serious adverse consequences, including rhabdomyolysis
(muscle injury) and death, from erythromycin-related or clarithromycin-related statin toxicity.
Herbal-drug interaction induced rhabdomyolysis
in a liposarcoma patient receiving trabectedin.
Washington, Aug 09 ( ANI ): HIITS- an exercise and weight-loss trend that involves alternating bouts of extremely vigorous exercise with brief rest periods- may be a superior way to slim down, but it can lead you to the hospital with rhabdomyolysis
, it has been revealed.
In one large cohort from Canada, older adults taking an implicated statin alongside erythromycin or clarithromycin were significantly more likely to be admitted to hospital with rhabdomyolysis
or acute kidney injury, and significantly more likely to die within 30 days than similar adults taking azithromycin instead.
CytoSorb(R) also removes myoglobin from blood, making it a potential treatment of rhabdomyolysis
Training emphasized the potential for liver effects and rhabdomyolysis
from statins, but 20 years of evidence now shows that statins do not cause chronic liver disease, rare patients get acute liver injury, and about 0.
Hypokalaemia is a widely known, though rare, cause of rhabdomyolysis