rheumatoid factor

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rheumatoid factor

n.
Any of several immunoglobulins that are found in the blood serum of many individuals with rheumatoid arthritis and in some individuals with other inflammatory diseases. A test for one or more of these factors is used in diagnosing rheumatoid arthritis.

rheu′matoid fac`tor


n.
an antibody that is found in the blood of many persons afflicted with rheumatoid arthritis and that reacts against globulins in the blood.
[1945–50]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.rheumatoid factor - autoantibody that is usually present in the serum of people with rheumatoid arthritis
autoantibody - an antibody acting against tissues of the organism that produces it
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References in periodicals archive ?
Incidence of serum rheumatoid factors in elder non-rheumatic individuals.
Association of anti-cyclic citrullinated peptide antibodies, anti-citrullin antibodies, and IgM and IgA rheumatoid factors with serological parameters of disease activity in rheumatoid arthritis.
8 Mart Mannik had earlier found that some 7s IgG rheumatoid factors self-aggregate to form larger immune complexes via hydrophobic interactions to become trapped within the synovial tissue.
Indeed, some 85 percent of people with the condition harbor so-called rheumatoid factors, which are antibodies that bind to antibodies.
His research has also established that certain rheumatoid factors, the most common antibodies in RA, are able to form immune complexes by self-association, without the presence of separate antigens.
We can therefore begin to ask what the antigen or antigens might be that produce IgGs reactive to 7 S or 19 S rheumatoid factors.