rofecoxib


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Related to rofecoxib: Etoricoxib
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Noun1.rofecoxib - a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004
Vioxx
Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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The uniform vote to keep celecoxib on the market and the split votes regarding rofecoxib and valdecoxib reflected the clear hazard seen with those two drugs.
FDA now reviewing panel's nod to COX-2s: celecoxib garnered nearly unanimous support; vote was more divided on rofecoxib and valdecoxib
Past studies indicated that aspirin and related anti-inflammatory drugs, which broadly inhibit cyclooxygenase enzymes, and drugs such as celecoxib (Celebrex) and rofecoxib (Vioxx), which selectively block COX-2 production, can prevent or stop certain cancers from growing.
Anti-inflammatories' cancer effects vary by brand and tissue type
But Vioxx Acute, made by Merck Sharp & Dohme Limited, contains rofecoxib which allows the stomach enzyme to keep working.
Health Zone: Bodytalk - Giving teeth a shot; What's new in health
has announced that it will pay $4.85 billion into a fund to settle claims that its cyclooxygenase-2 inhibitor rofecoxib (Vioxx) was responsible for causing myocardial infarction and stroke in patients who took the drug for pain.
Vioxx payout signals new FDA era
In the wake of the withdrawal of rofecoxib and the addition of a black box warning for antidepressants, the Food and Drug Administration has announced a plan aimed at strengthening its safety program for drugs.
FDA plans to strengthen Drug Safety program
(We were covering for another practice.) Her medications prior to admission were metformin, omeprazole, amitriptyline, and metoprolol, to which rofecoxib had recently been added.
Metformin in type 2 diabetes
HONOLULU -- Rofecoxib, a selective cyclooxygenase-2 inhibitor, significantly reduced the frequency of perimenstrual migraine headaches in a small, open-label trial.
Vioxx tied to drop in menstrual migraines
Newer prescription drugs, celecoxib and rofecoxib, target COX-2 only.
Effect on an enzyme may stop pain, lower fever. (Acetaminophen in Action)
Vioxx (rofecoxib) is the the first of a new generation of NSAIDs which also protect the lining of the stomach and intestines from everyday damage.
Family health: Arthritis drug breakthrough
Previously, the congressional watchdog agency reviewed the regulatory history of the drug Vioxx (rofecoxib), which was pulled from the market in 2004 after being linked to heart attacks and strokes.
FDA told to strengthen monitoring
A federal jury has rejected the lawsuit of Tennessee resident Anthony Dedrick, who claimed that his 2003 heart attack was caused by Vioxx (rofecoxib).
Things fail to go better with coke
The COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex) have been shown to provide equal pain relief compared with naproxen for patients with osteoarthritis.
Do acetaminophen and an NSAID combined relieve osteoarthritis pain better than either alone?

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