The sum of [Na.sup.+] and [Cl.sup.-] excretion was calculated for saluretic activity.
The saluretic activity and the natriuretic activity were calculated with the standard formula and presented in Table 3.
Prolonged Treatment with ESAH Induced Significant Saluretic Effect on Sham-Operated and 2K1C Plus OVT-Rats.
On the1stdayoftreatment, all animalstreatedwithESAH (30, 100, or 300 mg/kg) or HCTZ presented a significant increase in [Na.sup.+] and [Cl.sup.-] elimination, with saluretic index higher than 2.0 (Table 2).
(1983) 2-(Aminomethyl) phenols, a new class of
saluretic agents, 5.
The diuretic index (volume treated group/volume control group and saluretic (mmol/1 treated group/mmol/1 control group) was calculated.
Treatment Dose (mg/kg) Urine volume Diuretic (ml/100 g/24 h) [index.sup.a] Vehicle -- 4.1 [+ or -] 0.3 -- Furosemide 10 6.8 [+ or -] 0.2 *** 1.67 EEPam 125 6.36 [+ or -] 0.2 *** 1.54 EEPam 250 5.51 [+ or -] 0.2 * 1.34 EEPam 500 5.44 [+ or -] 0.4 * 1.32 Treatment [Na.sup.+] [K.sup.+] (mmol/l/100g/24h) (mmol/l/100g/24h) Vehicle 477 [+ or -] 10.1 428 [+ or -] 15.2 Furosemide 682 [+ or -] 23.8 *** 548 [+ or -] 21.8 *** EEPam 660 [+ or -] 14.1 *** 520 [+ or -] 7.0 *** EEPam 590 [+ or -] 37.9 ** 524 [+ or -] 16.3 *** EEPam 667 [+ or -] 38.6 *** 537 [+ or -] 17.7 *** Treatment Saluretic index (b) [Na.sup.+] [K.sup.+] Vehicle -- -- Furosemide 1.42 1.28 EEPam 1.38 1.21 EEPam 1.23 1.22 EEPam 1.39 1.25 Data are expressed as mean [+ or -] SEM.
The amount of [Na.sup.+] and [K.sup.+] was calculated as a parameter for the
saluretic activity.
Evaluation of diuretic,
saluretic and uricosuric actions of the tinctures and saponins from Anthemis tinctoria L.
Antiplasmodium Plasmodium falciparum strain DIO using the parasite lactate dehydrogenase (pLDH) assay Diuretic The Lipschitz test was used to determine the Diuretic and
saluretic activity in rats Cardiovascular Purified compounds on blood pressure and heart rate of anesthetized Wistar rats Anti-HIV Extracts and therein subfractions of A.
The sum of Na + and CT excretion was calculated as a parameter of
saluretic activity.
Water diuretics have a number of advantages over
saluretics that implement their diuretic effect through significant violations of water-salt metabolism, especially in the course administration.