A, a bioactive substance derived from natural plants, is a highly selective and effective agonist targeting Kappa opioid receptors (KOR).
Salvia divinorum and Salvinorin
A: an update on pharmacology and analytical methodology.
Localization of salvinorin
A and related compounds in glandular trichomes of the psychoactive sage Salvia divinorum.
The active ingredient, salvinorin
A, is typically measured by liquid chromatography at many reference laboratories.
Butterweck, "Salvia divinorum and salvinorin
A: an update on pharmacology and analytical methodology," Planta Medica, vol.
(21) The psychoactive agent in Salvia is salvinorin
A, a diterpene and selective kappa-opioid receptor agonist, which produces psychomimetc effects on ingestion of teas brewed from leaves, resembling the adverse effects caused by serotonergic agonists, selective serotonin reuptake inhibitors, or n-methyl-d-aspartate glutamate (NMDA) antagonists.
In the second study, Seva Katritch of the Scripps Research Institute in La Jolla, Calif., and colleagues looked at how the drug JDTic deactivates a kappa opioid receptor, which is turned on by the hallucinogen salvinorin
Possessing, with the intent to distribute, intoxicating substances, to include, but not limited to, Salvia Divinorum, Salvinorin
A, or the intoxicants "spice," "Ivory Wave," or any derivative thereof (see enclosure for a non-inclusive list of prohibited substances and derivatives);
At the molecular level, drugs like salvinorin
A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.
Salvia is an herb that contains the active ingredient salvinorin
The researchers conducted a double-blind trial in four psychologically and physically healthy hallucinogen-using adults, giving them 16 ascending doses of salvinorin
A and 4 intermixed placebo doses over 20 sessions and several weeks.