saquinavir


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Related to saquinavir: ritonavir, nelfinavir, Saquinavir mesylate

sa·quin·a·vir

 (sə-kwĭn′ə-vîr)
n.
A protease-inhibiting drug given in the form of its mesylate, used usually in combination with other drugs to suppress the replication of HIV.

[saquin- (perhaps alteration of (i)soquin(oline) : iso- + quinoline) + a(nti)vir(al).]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.saquinavir - a weak protease inhibitor (trade name Invirase) used in treating HIV
protease inhibitor, PI - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
Translations

saquinavir

n saquinavir m
References in periodicals archive ?
(4) Therefore, the package insert for Invirase states in a prominent black-boxed warning: "Invirase (saquinavir mesylate) capsules and Fortovase (saquinavir) soft gelatin capsules are not bioequivalent and cannot be used interchangeably.
CANADA -- Researchers monitored 10 healthy volunteers to determine a link between garlic intake and the protease inhibitor saquinavir.
The researchers gave the protease inhibitor saquinavir to HIV-free volunteers.
saquinavir (Fortovase, Invirase) levodopa (Atamet, Larodopa) Treats Parkinson's Disease.
The drugs in this class include: indinavir (Crixivan[R]), saquinavir mesylate (Invirase[R]), nelfinavir mesylate (Viracept[R]), ritonavir (Norvir[R]), saquinavir (Fortovase[R]), and amprenavir (Agenerase[R]).
Examples of protease inhibitors already in use include saquinavir, nelfmavir, and indinavir.
* HIV-I protease inhibitors like indinavir (Crixivan), ritonavir (Norvir), and saquinavir (Invirase)?
Indinavir, nelfinavir, ritonavir, saquinavir, efavirenz and nevirapine: Used in HIV patients.
Patients generally take a combination of AZT, 3TC, and one of the protease inhibitors such as ritonavir, indinavir, or saquinavir, says Zhang.
* Saquinavir mesylate (Fortovase [soft gel capsule], Invirase [hard gel capsule], SQV), Hoffmann-La Roche
Currently, Nelfinavir is resisted; changing two letters at RT 151 resists D4T, and changing one at PRO 90 resists Saquinavir.
"New anti retro-viral drugs, such as Indnavir, Ritonavir and Saquinavir, are really helping patients.