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A potent neurotoxin produced by certain dinoflagellates that accumulates in shellfish feeding on these organisms and consequently causes food poisoning in humans who eat the shellfish.

[New Latin Saxi(domus gigantēus), butter clam (in which the toxin was first recognized) (from Latin saxum, stone; see saxifrage) + toxin.]


a poisonous alkaloid (C10H17N7O4) produced by dinoflagellates of the genus Gonyaulax that build up in molluscs and cause food poisoning in humans


(ˌsæk sɪˈtɒk sɪn)

a neurotoxin produced by the dinoflagellate Gonyaulax catenella, the causative agent of red tide.
[1960–65; < New Latin Saxi(domus), a clam genus infected by the dinoflagellates (Latin sax(um) stone + -i- -i- + domus house) + toxin]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.saxitoxin - a powerful neurotoxin produced by certain dinoflagellates found in red tides; it can accumulate in mollusks that feed on the dinoflagellates and cause food poisoning to humans
neurolysin, neurotoxin - any toxin that affects neural tissues
References in periodicals archive ?
Detections included microcystin (eight of eight investigations), anatoxin-a (three of four), saxitoxin (two of five), and cylindrospermopsin (two of five).
During an NIH-funded study, the researchers used specially designed fat-based particles called liposomes to package saxitoxin, a potent anesthetic, and produced long-lasting local anesthesia in rats.
Two potent neurotoxins, tetrodotoxin in riparian stream environments and saxitoxin in coastal ocean environments, are introduced into communities by limited sources as a means of chemical defense.
We propose characterizing this food poisoning syndrome as saxitoxin puffer fish poisoning (SPFP) to distinguish it from PFP, which is traditionally associated with tetrodotoxin, and from PSP caused by STXs in shellfish.
Lyngbya wollei is a filamentous, mat-forming cyanobacterium that has been shown to produce saxitoxin, a paralytic shellfish poison.
Certified reference materials (CRM) used were decarbamoyl saxitoxin (dcSTX), neosaxitoxin (NEO), saxitoxin di-hydrochloride (STX), gonyautoxins 1-5 (GTX1-5), A'-sulfocarbamoyl-gonyautoxins 2 and 3 (C1&2), decarbamoylneosaxitoxin (dcNEO), and decarbamoyl gonyautoxins 2 and 3 (dcGTX2&3).
The toxicity level in the bay reached 74 microgram saxitoxin per 100 grams of shellfish meat, or higher than the regulatory limit of 60.
However, saxitoxin levels were reported to have been higher in shellfish in the region during spring 2011 than in previous years (Kate Sullivan, University of Alaska Southeast, personal communication, 2011), indicating that the increase in the number of cases might not have been a surveillance artifact.
Here, the guanidine alkaloids tetrodotoxin (TTX) and saxitoxin (STX) are used to illustrate recent research findings that coalesce neurobiological and ecological paradigms.
Harmful algal blooms that release biotoxins, such as saxitoxin and domoic acid, have led to several recent beach closures for shellfish harvesting [Commission on Asian Pacific American Affairs (CAPAA) 2004; Washington Department of Health (WADOH) 2004].
Shellfish toxicity level in the bay reached 74 microgram saxitoxin (AugSTXeg)/100 grams of shellfish meat, which was beyond the regulatory limit of 60, according to the advisory.